I-immunoglobulin yomuntu evamile iyisidakamizwa sokuvimbela izidakamizwa esibhekwa njengeqembu lama-immunostimulating and immunomodulating agents. Ikhishwa egazini labanikeli abanempilo abaye bahlolwa izibalo ezikhethekile zemitholampilo kanye nezivivinyo zama-laboratory futhi abanakho ubufakazi bokutheleleka kwegazi (ikakhulukazi, ukutheleleka ngegciwane lesandulela ngculazi, isifo sofuba C kanye noB).
Ingxenyana eyinhloko yalesi sidakamizwa yingxenyana ekhunjulwa ngamagciwane eprotheyini yegazi, ene-immunoglobulin G futhi iqukethe i-immunoglobulin M ne-immunoglobulin A emazingeni amancane. Ukulungiselela kuhlanjululwe kahle, kugxilwe futhi kungenwa amagciwane ngesikhathi sokukhiqiza. I-immunoglobulin yomuntu engavamile ayiqukethe ama-preservatives nemithi elwa namagciwane, njengoba isiqiniseko sine-glycine.
Ukukhululwa kwefomu kanye nendlela yokusebenzisa i-immunoglobulin yomuntu evamile
Imithi ingakhiwa ngendlela yesisombululo, ihlanganiswe ngama-ampoules, noma i-lyophilizate yokwenza isisombululo, ihlanganiswe ngamabhodlela. Ngendlela ekhethiwe ayikho embala noma ephuzi, ecacile. I-lyophilisate ye-immunoglobulin yomuntu evamile iyinqwaba emhlophe emhlophe. I-immunoglobulin yomuntu isetshenziselwa ukuphathwa kwe-intramuscular (injections) nokuphathwa kwe-intravenous (dropper).
Izakhiwo ze-immunoglobulin yabantu evamile
Isidakamizwa sinempahla ye-immunoglobulin G, etholakala kubantu abanempilo. Uma kuqaliswa, imiphumela elandelayo ifinyelelwa:
- ukuphindwa kabusha kwama-anti-gribal anti-IgG, okusiza ukunciphisa ingozi yokuthuthukisa izifo ezehlukene;
- ukuqala kabusha kwezinga eliphansi le-IgG kumanani avamile;
- ukwanda okungekho okuqondile komzimba womuntu;
- ukususa kanye neutralization of ahlukahlukene amabhaktheriya, amagciwane kanye nezinye amagciwane ezithathelwanayo.
Izinkomba zokusetshenziswa kwe-human immunoglobulin evamile:
- isifo sofuba sokuzalwa kwesifo somzimba;
- i-immunodeficiency variable ejwayelekile;
- i-iatrogenic immunodeficiency;
- i-chronic lymphocytic leukemia;
- i-myeloma;
- purpura ye-thrombocytopenic ye-immune originally engozini yokwanda kwegazi;
- Isifo sikaKawasaki;
- ukuguqulwa kwamathambo;
- izifo ezinzima zemvelaphi ehlukahlukene;
- i-meningitis ye-bacterial;
- I-Guillain-Barre syndrome;
- ukuxoshwa kwe-polyneuropathy evuvukalayo ngesimo esingapheli;
- i-hemolytic anemia;
- i-thrombocytopenia yemvelaphi yomzimba;
- i-autoimmune neutropenia;
- i-aplassia yesinxele ebomvu ye-hematopoiesis;
- i-myasthenia gravis ;
- ukuphutha kwesisu okungajwayelekile;
- isifo sofuzo A;
- isingenisi;
- i-poliomyelitis;
- umkhuhlane;
- ukukhwehlela ukukhwehlela;
- ukutheleleka kwamadoda, njll.
Imiphumela emibi kanye nokuphikisana kwe-human immunoglobulin evamile
Imiphumela emibi yokuthatha i-immunoglobulin yomuntu evamile:
- ukushisa komzimba okwandisiwe;
- ubuhlungu ekhanda;
- isicasuli;
- i-tachycardia;
- ubomvu endaweni yomjovo;
- ukujuluka, njll.
Ukuqhathaniswa kokusungulwa kokujwayelekile kwe-immunoglobulin yomuntu:
- ukucindezeleka komuntu ekuziphatheni kwegazi, imikhiqizo yegazi;
- ukutholakala kwama-antibodies ku-IgA.
Ngokunakekelwa, imithi isetshenziswa uma:
- ukukhulelwa, ukubeletha;
- isifo sikashukela mellitus;
- ukukhushulwa kwezinqubo zokwelapha;
- ukwehluleka kwenqunu;
- i-nephrite;
- i-migraines;
- ukuhluleka kwenhliziyo okungapheliyo;
- izifo ze-immune zegazi;
- i-collagenosis, njll.
Futhi, uma usebenzisa lesi sidakamizwa, kubhekwa ukuthi ukuphathwa kwayo kwancipha okwesikhashana umphumela wokugoma okuphikisana ne-pathologies efana ne-rubella, isisimungumungwane, izimpungushe nezinkukhu.