I-Sjogren's syndrome yisifo esizimele esisodwa esiholela ekulimaleni komzimba kuzicubu ezixhunyiwe. Kusukela ohlelweni lwe-pathological, izinhlayiya ze-exocrine - izigulane eziqhakazile nezinyembezi - zihlupheka kakhulu. Ezimweni eziningi, lesi sifo sinenkambo engapheliyo.
I-Sjogren's Syndrome - siyini lesi sifo?
Esikhathini esiyinkimbinkimbi sezimpawu zesifo esomile okokuqala ngenye indlela ukunakekelwa kwakhokhwa yi-ophthalmologist isiSweden uShegren eminyakeni engaphansi kwekhulu edlule. Uthole isibalo esikhulu seziguli zakhe eza kuye ngezikhalazo ezomile emehlweni, ezinye izimpawu ezifanayo: ukuvuvukala okungapheli kwamalungu kanye ne-xerostomia - owomile we-mucosa yomlomo. Ukuqaphela abanye abanentshisekelo nodokotela kanye nososayensi. Kwakukhona ukuthi lokhu ukukhubazeka kuvamile futhi ukulwa nakho kudinga ukwelashwa okuqondile.
I-Sjogren's syndrome - iyini? Lesi sifo esingenasifo esizimele sitholakala ngokumelene nesizinda sokwehluleka kwesistimu yomzimba. Umzimba uthatha amangqamuzana awo amangqamuzana angaphandle futhi uqala ukuthuthukisa ama-antibodies kubo. Ngokumelene nalesi sizinda, inqubo yokuvuvukala iqala, okuholela ekunciphiseni emsebenzini wezingqungquthela zokwehliswa kwangaphandle - ngokuvamile okuvakalayo nokulahla.
I-Sjogren's Syndrome - Izimbangela
Ukuze usho ngokucacile ukuthi kungani izifo ze-autoimmune zikhula, imithi ayikwazi okwamanje. Ngakho-ke, lapho i-dry syndrome ye-Sjogren ivela khona kuyimfihlakalo. Kuyaziwa ukuthi izakhi zofuzo, i-immunological, i-hormonal nezinye izinto zangaphandle zihlanganyela ekuthuthukiseni lesi sifo. Ezimweni eziningi, ama-virus afana ne-cytomegalovirus, i-Epstein-Barr, i-herpes, noma izifo ezifana ne-polymyositis, i-systemic scleroderma, i-lupus erythematosus, i-rhumatoid arthritis iyisisusa ekuthuthukiseni lesi sifo.
I-Primary Sjogren's Syndrome
Kunezinhlobo ezimbili eziyinhloko zokugula. Kodwa kunjalo cishe. Ukumiswa kwamabhungane omuncu kuzo zombili izimo kuvela ngenxa yokungena kwe-lymphocytic yezingqungquthela ze-exocrine eceleni kwendlela yokugoma kanye nokuphefumula. Uma lesi sifo siqala njengesifo esizimele futhi akukho lutho oluqala ukubonakala kwalo, yilesi sifo esiyinhloko seSjogren.
I-Secondary Sjogren's Syndrome
Njengoba umkhuba ubonisa, kwezinye izimo, lesi sifo senziwa ngokumelene nesizinda sezinye izifo. Ngokwezibalo, i-secondary syndrome eyomile itholakala kuma-20 - 25% weziguli. Kufakwa uma lesi sifo sihlangabezana nezinkinga zezinkinga ezifana ne-rheumatoid arthritis, i-dermatomyositis, i-scleroderma kanye nezinye ezihambisana nezilonda zamathishu ahlangene.
I-Sjogren's syndrome - izimpawu
Zonke izibonakaliso zalesi sifo zihlukaniswe zibe yizinhlayiya futhi zine-extra-iron. Ukuthi i-Sjogren's syndrome isakazeke ezindlebeni ezilahlayo kungaqondakala ngokuzwa okushisayo, "isihlabathi" emehlweni. Abaningi bakhononda ngejwabu leso elibizayo. Ngokuvamile amehlo aphendukile, futhi emagumbini awo aqoqa imithi ebomvu evumayo. Njengoba lesi sifo sithuthuka, isithombe se-photophobia siqala, iso lishaya ngokubonakalayo lincane, ubuciko obubonakalayo buya phansi. Ukwanda kwezigulane ezibulalayo kuyinto engavamile.
Izici zezimpawu zesifo se-Sjogren, esathinta izigulane ezisezingeni eliphansi: emanzini omile emlonyeni, emngceleni obomvu, izindebe. Ngokuvamile, iziguli zihlaselwa , futhi, ngaphezu kwezingqungquthela ezisezingeni eliphansi, ezinye izigulane eziseduze nazo zanda. Ekuqaleni, lesi sifo sibonakala ngokuzikhandla ngokomzimba noma ukucindezeleka ngokomzwelo. Kodwa ngokuhamba kwesikhathi ubomvu buba unomphela, izindebe zimbozwe nge-crusts eziphazamisayo, okwandisa ingozi yokujoyina isifo sofuba.
Ngezinye izikhathi, ngenxa yokomisa ku-nasopharynx, ama-crusts aqala ukwakha emakhaleni nasempilini, okungaholela ekutheni i-otitis kanye nokulahlekelwa kwesikhashana kokuzwa. Uma izintambo ze-pharynx nezamazwi zidlulile kakhulu, kukhona ukugcoba nokugcoba. Kanti futhi kwenzeka ukuthi ukuphulwa kokugwinya kuholela ekutheni igastritis i-atrophic. Ukuxilongwa kubonakaliswa yisicefe, ukwanda kwesifiso, isisindo esifundeni se-epigastric ngemuva kokudla.
Ukubonakaliswa kwe-extragenital yesimiso esiyinkimbinkimbi se-Sjogren's syndrome kubukeka kanje:
- ubuhlungu obuhlangene;
- ukuqina kwemisipha namalungu ekuseni;
- ubuthakathaka bemisipha;
- ukuqhuma okuncane kwegazi okwenzeka ngokumelene nesizinda sezilonda zamasongo;
- i-neuritis ye- facial or trigeminal neva;
- ukuqhuma kwesifo esiqhumeni esiqwini kanye nemikhawulo;
- ukoma kwesifazane.
I-Sjogren's syndrome - ukuhlonza okuhlukile
Incazelo yesifo ngokuyinhloko isekelwe ekubeni khona kwe-xerophthalmia noma i-xerostomia. Lezi zinsuku zitholwa nge-sialography, ukucaciswa kwe-parotid kanye ne-salivary gland biopsy. Ukuze kuhlolwe i-xerophthalmia, ukuhlolwa kwe-Schirmer kwenziwa. Omunye umkhawulo womugqa wephepha ohlungiwe usekwe ngaphansi kwejwabu leso eliphansi futhi ushiye okwesikhashana. Kubantu abanempilo, emva kwemizuzu engaba ngu-5, cishe u-15 mm we-strip izoba yimbi. Uma ngabe i-Sjogren's syndrome iqinisekisiwe, ukuxilongwa kubonisa ukuthi akugcini kuka-5 mm wet.
Ekuxilongweni kokuhlukana kubalulekile ukukhumbula ukuthi i-NLS ingahlakulela ngokufana nalezi zifo ezifana ne-autoimmune thyroiditis, i-percinosis anemia, isifo sezidakamizwa. Incazelo ye-primary syndrome eyomile yenziwa kakhulu ngokutholakala kwamagciwane omzimba we-SS-B. Kunzima kakhulu ukuthola ukuthi isifo sikaSjogren sinesifo samathambo, ngoba umonakalo ohlangene uqala isikhathi eside ngaphambi kokubonakala kwezimpawu zomile.
I-Sjogren's syndrome - ukuhlolwa
Ukuthola ukuhlolwa kwesifo kuhilela ukuqhuba ukuhlolwa kwelabhorethri. Uma kutholakala ngesifo sika-Sjogren, ukuhlaziywa kubonisa cishe imiphumela elandelayo:
- Esivivinyweni segazi jikelele, ukusheshiswa kwe-ESR, inani le-anemia nelincane elimhlophe selibalo legazi lizimisele.
- I-OAM ibonakala ngokukhona kwamaprotheni.
- Iprotheyini ibuye iphakanyiswe ekuhlaziyweni kwegazi ngegazi. Ngaphezu kwalokho, lolu cwaningo lwembula izihloko eziphezulu zesifo se-rheumatoid.
- Ukuhlolwa kwegazi okhethekile mayelana nokutholakala kwama-antibodies ku-thyroglobulin ngo-35% kubonisa ukwanda kokugxila kwabo.
- Imiphumela ye-salivary gland biopsies iqinisekisa izimpawu ze-Sjogren's syndrome.
I-Sjögren's Syndrome - ukwelashwa
Lena inkinga enkulu, kodwa ayibulali. Uma unake izibonakaliso zayo ngesikhathi futhi uma uthola ukuthi ukwelashwa kwesifo se-Sjogren sekuqalile, ungahlala nayo, uzizwa ukhululekile nayo. Into esemqoka iziguli akumele zikhohlwe ukubaluleka kokuphila okunempilo. Lokhu kuzokusiza ukuqinisa imishanguzo, ngeke kuvumele inqubo ye-pathological ukuba ihlakulele ngenkuthalo futhi inciphise kakhulu ingozi yezinkinga.
Kungenzeka yini ukuphulukisa i-Sjogren's syndrome?
Lapho ukuxilongwa kuqinisekiswa, isiguli sithola izincomo zokwelapha. I-Sjogren's syndrome iyaphathwa ngempumelelo namuhla, kodwa kungakabonakali ukususa lesi sifo ngokuphelele. Ngenxa yalesi sizathu, kwenziwa ukwelashwa okuphawulekayo kuphela. Imigomo yokuhlola ikhwalithi yokwelapha yinto evamile yokubonakaliswa kwemitholampilo yesifo. Uma zonke izinhloso zokwelapha zisiza, izinkomba ze laboratory kanye nesithombe sakhe esithuthukisayo zithuthukisa.
I-Sjögren's Syndrome - Izincomo Zomtholampilo
Ukwelashwa kwe-syndrome eyomile kuhilela ukunciphisa izimpawu futhi, uma kunesidingo, ukulwa nesifo se-autoimmune yangemuva. Ngaphambi kokwelashwa kwe-Sjogren's syndrome, ukuxilongwa kwenziwa ngempela. Ngemuva kwalokho, njengombuso, izindlela ezinjalo zisetshenziswa:
- i- Prednisolone ye- glucocorticoid (uhlelo kanye nomthamo kunqunywe ngabanye kuye ngokuthi ubuhlungu be-syndrome nobunzima bezimpawu zayo);
- ama-angioprotectors - i-Parmidin, i-Solcoseryl;
- i-immunomodulator Splenin;
- i-anticoagulant Heparin;
- I-Contrikal noma i-Trasilol - izidakamizwa eziyeka ukwenziwa kwama-enzyme e-proteolytic;
- Zioostatics - I-Chlorbutin, i-Azathioprine, i-Cyclophosphamide (ngokuyinhloko batusa ukuthatha i-glucocorticoids).
Ukuze ususe umlomo owomile, hlambulula. I-eye syndrome eyomile iphathwa ngokugxiliswa kwe-saline, i-Hemodesis. Ama-tubes nama-trachea omile abomile angaphathwa nge- Bromhexine . Ngokuvuvukala kwe-Dimexide ye-glands, i-Hydrocortisone noma i-Heparin bayalwela. Ngezinye izikhathi umlomo owomile ekutholeni i-Sjogren's syndrome kuholela ekuthuthukiseni izifo zamazinyo. Ukuze uzivimbele, udinga ukunakekelwa kokuhlanzeka komlomo.
Isifo sikaSjogren - ukwelashwa ngamakhambi abantu
I-syryrome eyomile iyinkimbinkimbi yezimpawu nezimpawu. Ngabo bonke kungcono ukulwa ngokujwayelekile. Kodwa ngezinye izikhathi nge-Sjogren's syndrome, izindlela zomuntu ezisetshenziselwa usizo olufanayo ukuthuthukisa isimo sesiguli. Ezinye iziguli, isibonelo, isaziso sokuthi amaconsi e-eye asuka ku-dill namazambane amazambane asebenza kangcono kunamanzi asebenzisa imithi ebulala imithi.
I-decoction ye-herbal yokuhlanza
Izithako:
- chamomile izimbali - 1 isipuni;
- amaqabunga ama-sage - 1 tbsp. l.;
- amanzi - ingilazi eyodwa.
Ukulungiselela nokusebenzisa:
- Hlanganisa amahlumela futhi ugaye kancane.
- Amanzi abilayo futhi uthele ingxube eyomile.
- Umuthi udinga ukuphuza imizuzu engu-40.
- Ngemuva kokuhlunga ilungele ukusetshenziswa.
I-Sjogren's syndrome - ukubikezela
Lesi sifo siqhubeka ngaphandle kokusongela empilweni. Kodwa ngenxa yakhe, izinga lempilo yeziguli liyehla kakhulu. Ukwelashwa kusiza ukuvimbela izinkinga futhi kugcina amandla okusebenza kwabantu abadala - I-Sjogren's syndrome ezinganeni kuyinto engavamile kakhulu. Uma ukwelashwa kungaqali, lesi sifo singakhula sibe yindlela enzima, okuyilapho, lapho ukutheleleka kwesibili, njenge- bronchopneumonia , sinusitis noma i-tracheitis ephindaphindiwe, ngezinye izikhathi kuholela ekukhubazekeni.