I-Prednisolone ngendlela yamathebulethi yisidakamizwa esivamile se-hormonal, esinqunywe njengengxenye yezokwelapha eziyinkimbinkimbi zezifo ezihlukahlukene. Isidakamizwa sinomthelela onamandla kakhulu futhi sinombono omkhulu wokuphikisana, ngakho-ke inqunyelwe iziguli ngokuqapha futhi emva kokuhlolwa kokuqala.
Ukwakhiwa kanye nesenzo samakhemikhali amaphilisi Prednisolone
Into esebenzayo enkulu kulokhu kulungiselelwa i-prednisolone, i-analogue yokwenziwa kwamahomoni cortisone ne-hydrocortisone eyimfihlo yi-cortex ye-adrenal (i-tablet eyodwa iqukethe 5 mg wezinto ezisebenzayo). Izingxenye ezisizayo ziyi:
- ubisi ushukela;
- isitashi;
- i-calcium stearate.
Isidakamizwa sisheshe sithathwe kusukela emathangeni omzimba, singene egazini futhi, ngokusebenza komuthi osebenzayo, sikhiqiza umphumela wokuphefumula olandelayo:
- i-immunosuppressive (ngenxa yokuvimbela ukukhululwa kwama-cytokines kusuka ku-lymphocytes nama-macrophages);
- Ukulwa nokuvutha (ngokuyinhloko ngokubamba iqhaza kwama-cytosolic receptors);
- i-antiproliferative (ngenxa yokuvimbela ukukhiqizwa kwe-nucleic acid emasethini okugcwala kwe-epidermis kanye nama-fibroblast of the dermis);
- i-antiallergic (ngokunciphisa inani lamabhasiphi kanye nokuvimbela ngokuqondile ukuhlanganiswa nokukhiqizwa kwezinto eziphilayo ezisebenzayo);
- ukunciphisa ukwandiswa kwezicubu ezithinta izifo nokukhula kwamangqamuzana omzimba;
- ukunciphisa amandla e-capillary;
- amazinga weglucose wegazi;
- ukujwayela ukuphefumula nge- edema angioneurotic ;
- ukuhoxiswa kokubamba kanye nobuhlungu.
Umthelela wokwelashwa uthola amahora ama-1.5 ngemuva kokuthatha umuthi bese uhlala amahora angu-18 kuya kwangu-36. Kumele kucatshangelwe ukuthi umphumela onobuthi emzimbeni we-prednisolone engakaqediwe kungenzeka uma kwenzeka ukunciphisa inani lamaprotheni e-plasma yegazi. Isidakamizwa sidonswa emcinini nasezindlini, ukubola, ikakhulukazi esibindi.
Izinkomba zokusebenzisa amaphilisi e-Prednisolone
Ngokwemiyalelo ye-Prednisolone Nycomed (uhlobo lwephilisi - iphilisi), izinkomba eziyinhloko zalolu mithi ziyi:
- ukusabela okusheshayo kwe-allergic;
- i-asthma ye-bronchial;
- isimo se-asthmatic;
- ukusabela kwe-thyrotoxic kanye nenkinga ye-thyrotoxic (ukuvimbela nokwelashwa);
- ukungakwazi kahle kwe-adrenal;
- i-hepatitis acute;
- i-cirrhosis yesibindi;
- uketshezi ngamanzi okushisa, njll.
I-Prednisolone nayo inqunyelwe ukunciphisa izimpawu noma ukuvimbela ukuqhubeka kwe-pathology kwi-rheumatoid arthritis, i-lupus erythematosus, i-scleroderma, i-rheumatism, njll. Amathebulethi okuthiwa i-Prednisolone ngezinye izikhathi anqunyelwe i-oncology (phakathi nenkambo ye-chemotherapy), okusiza ekuvimbeleni ukuhlanza nokuhlanza izinhlanzi.
Ngithatha kanjani i-Prednisone kumaphilisi?
Isidakamizwa sithathwa ngomlomo ngesikhathi noma ngemuva kokudla, ngamanzi. Amaphilisi okulinganisa i-Prednisolone, ekhethwe udokotela ngabanye. Njengomthetho, isilinganiso sokuqala singama-20 - 30 mg ngosuku (izikhathi ezingu-2-3), kanti inani lemithi liyancipha kancane kancane.
Imiphumela emibi ye-Prednisolone kumaphilisi:
- ukulala;
- ukukhathazeka;
- ukuvuvukala;
- ukwanda kwengcindezi yegazi;
- i-amenorrhea ;
- i-alkalosis;
- ukwanda kwesisindo somzimba;
- ukwandiswa kwegazi kwegazi;
- ukwanda kwe-acidity yejuji yesisu, njll.
Ukungafani kokuthatha amathebulethi i-Prednisolone:
- ukucindezeleka komzimba;
- ukuhluleka kwezinso;
- i-peptic ulcer;
- isifo sikashukela mellitus;
- endocarditis yebhaktheriya;
- Isifo sika-Itenko-Cushing;
- i-osteoporosis;
- isifo sofuba;
- i-syphilis;
- i-psychoses;
- ukukhulelwa kanye nokulahlwa.