Igama elithi "ama-stem cells" ekudleni libhekisela ezakhiweni zamaselula ezingapheli, ezingafani. Banekhono lokuzivuselela, ukuhlukana ngokusebenzisa i-mitosis nokuguqulwa zibe ngamaseli ezinye izitho nama-tissue, babuyiselwe ngokuphelele.
Kungani ugcine igazi lomthambo we-umbilical?
Ukuzwa mayelana nezindlela zokwelapha ngama-stem cells, iziguli zivame ukuthakazelisa ukuthi yini i-blood strord blood and why it. Ukubaluleka kwalokhu kutholakala kwezinto eziphilayo kubangelwa ukuthi ekubunjweni kwalo kuqukethe amaseli asebenzayo asebenzayo, afanele kakhulu ukwelashwa. La maseli egazi asetshenziselwa ukuguqulwa kwezifo ze-transplanatology kanye nokwelashwa kwezifo ezinjengalezi:
- i-leukemia ;
- izifo ezikhukhumayo ze-immune;
- izifo zesistimu ye-musculoskeletal;
- isifo sikashukela.
Ukwelashwa kwamajoyina ngama-stem cells
Ukwelashwa kwe-arthrosis ngama-stem cells akusizi nje kuphela ukulahla izimpawu eziyinhloko zesifo, kodwa futhi kubuyiselwa izicubu zethambo. Ama-stem cells aphinde aboniswe ukuthi ayasebenza ekwelapheni izifo ezizimele. Ngokuhlukunyezwa okunjalo, isimiso somzimba sokuvikela amasosha sikhona njalo sihlasela amajoyina, sichitha izicubu zomzimba. Imithi esetshenziselwa okwesikhashana ukunciphisa izinqubo zokuvuvukala, ukunciphisa ubukhulu bezinhlungu.
Ukuyingqayizivele kokusetshenziswa kwama-stem cell ekunakekeleni izifo ezihlangene yilokhu:
- ukuvuselelwa okusebenzayo kwezakhi ezihlangene ezimele (ukungena emzimbeni, amangqamuzana ahlukanise, esikhundleni sezingxenye ezonakalisiwe zezicubu zomzimba);
- ukuvuselela amasosha omzimba, ukuvikela umzimba ekuhlaselweni kwamagciwane;
- ukuthuthukiswa kwezintambo zezintambo kanye nokujwayelekile kwesimetabolism;
- ukuheha ama-cytokines - izici zokulwa nokuvuvukala;
- izicubu ze-trophic nokujwayelekile kwe-metabolism.
Ukwelashwa ngama-stem cells wesifo sikashukela
Isifo sikashukela sibhekisela ezifweni ezine-disabetes disorder. Ukwelashwa ngamaseli ase-stem kuthuthukisa kakhulu isithombe salokho okwenzekayo. Kulokhu, izakhiwo zamaselula ezihlanganiswa ngumzimba wesiguli ziyasetshenziswa. Belwa imbangela yesifo sikashukela ngokunciphisa i-hyperglycemia. Njengoba kuboniswa ukuvivinywa kwemitholampilo, le ndlela iphumelela ekulwa no-hypoglycemia - kunciphisa umphumela we- coma ye- hypoglycemic , ukushaqeka.
Inkambo ye-stem cell therapy ihilela isingeniso emzimbeni ngokusebenzisa umthambo we-pancreatic ngosizo lwesikhala. Ukuvuna okokuqala izinto ezivela emzimbeni we-aliac wesiguli ngenaliti encane ngaphansi kwe-anesthesia yendawo. Inqubo ihlala imizuzu engu-30. Amaseli aqoqwe athunyelwa ebhokisatri, lapho ikhwalithi yamaseli inqunywa khona, ukuhlolwa kwabo nokubala. Kuphela emva kwalokhu, amaseli we-stem alungele ukungeniswa emzimbeni. Indawo yokuphatha ikhethwe ngamunye (ngaphakathi, imisipha yomlenze, umthambo we-pancreatic).
I-Stem Cell Treatment for Stroke
Ukushaywa isisu kubhekisela ezifweni ezihambisana nokusabalalisa kwe-cerebral ekhubazekile. Izindawo ezithintekile ze-pathology azitholi oksijini okwanele, okuholela emiphumeleni engenakuguqulwa ngokungabikho kokwelashwa okufanele. Umgomo wezokwelapha ukubuyiswa okuphelele kwezindawo ezilimele zezincubu zobuchopho. Imiphumela yokuqala emihle ingabonakala emva kwezinyanga ezintathu ngemuva kokusungulwa kwamaseli e-stem.
Ukuze wenze ukukhwabanisa, kungenzeka ukusebenzisa kokubili amangqamuzana e-stem kusuka emthonjeni wegazi, nalawo athathwa esitokisini se-iliac sesiguli ngokwakhe. Ngaphambi kwalokho kuyadingeka ukuqhuba i-anesthesia yendawo. I-sampuli yamathambo eqoqiwe ithunyelwa ebhokisatri, lapho iqhutshwa khona ngokucophelela - ukuhlukaniswa kwamaseli e-stem. Kulokhu, amasampuli awahlangani nomoya ukugwema ukutheleleka.
Ukwethulwa kweminye imikhawulo elandelanayo yalokho kufezwa ngokugqunywa kwe-lumbar . Izakhiwo ze-cell zijojowe ngqo ku-cerebrospinal fluid ezungeze intambo yomgogodla. Indawo yangaphambili ye-anesthesia yomjovo wendawo. Inqubo ithatha imizuzu engu-30. Ngamahora 3-4 isiguli singaphansi kokuqondiswa odokotela, bese siya ekhaya.
Ukwelashwa ngama-cell stem cells
I-umbilical cord igazi iye yazibonakalisa ngokuphelele ekwelapheni izifo eziphilayo. Ehlangene namaseli akhe amancane asetshenziselwa ukuvuselelwa kwezitho ezilahlekile zezitho ngokuhlukaniswa okusheshayo nokuhlukaniswa. Umphumela awunawo uhlobo lwesigaba esisodwa - umphumela wokwelashwa ungabonakala ngemva kwezinyanga ezingu-1-2. Ngokufanayo, inkambo enkulu yokwelashwa ehlose ukuvimbela ukusabalalisa kokugxila kwe-tumor kwenziwa.
Ukwelashwa ngama-stem cell atrophy we-optic nererve
Ukusetshenziswa kwama-stem cells ku-ophthalmology kuhilela ukubuyiselwa kwamasayithi we-retina eyonakalisiwe yeso, kodwa futhi nokubuyiselwa kokusebenza kwe-nertic optic. Amaseli asetshenzisiwe ngokushesha aya ezindaweni ezilimazayo, ahlotshaniswa nezicubu, ahlukanise futhi aguquke abe izakhi zezempilo ezinempilo zoluhlobo oludingekayo. Inqubo yokwethulwa kwamaseli e-stem yenziwa ngokuqondile esweni. Ukuphathwa okunjalo kungasetshenziselwa ezinye izifo zesimiso sombono:
- i-taperotorhinal dystrophy;
- i-astigmatism ;
- ukuguqulwa kwamagciwane.
Ukuvuselelwa Kwamaselula Esimangalo
Ekuqaleni, ukufakelwa kwe-stem cell kwenziwa kuphela ngenhloso yokuvuselelwa. Le ndlela ibizwa ngokuthi i-revitalization (kusukela eLatini - ukubuya ekuphileni) futhi ihilela ukubuyiswa komonakalo wokuqala ezithombeni nasezikhunjini ngenxa yezinguquko ezihlobene nobudala. Imfundiso eyinhloko yokubangela ukuguga kwemvelo namuhla ibhekwa njengokunciphisa echibini lama-stem cells okwenyuka ngesikhathi esisodwa emandleni abo.
Ucwaningo lubonisa ukuthi ukuguga emzimbeni kuqaliswa eminyakeni engama-30. Kulokhu, umzimba wesifazane, ngokusho kososayensi baseMelika, uhlala unempilo enhle kuze kube yiminyaka engu-44, futhi amadoda - kuze kufinyelele ku-40. Ukufakelwa kwezitshalo zama-stem cells kunciphisa kakhulu izinga lezinqubo ezilimazayo emzimbeni. Inombolo yezinqubo kanye nevolumu yezinto ezifakiwe zeselula zikhethwe ngokuzikhethela. Ukuze uthole ngcono, amangqamuzana e-autologous, okungukuthi, amaseli wesiguli, afaneleka kakhulu.
Ukuqoqwa nokugcinwa kwegazi lomthambo we-umbilical
Owesifazane ngamunye osebenzayo angaqeda isivumelwano sokuqala nomtholampilo ukuqoqwa kanye nokugcinwa kwegazi emgqeni we-umbilical. Ukulondolozwa kwekhanda legazi kwenziwa ezimweni zamabhange akhethekile - izikhungo zezokwelapha ezihlinzeka ngemisebenzi ekhethekile. Ubude besitoreji bubekwa yisiguli ngokwakhe, ngakho le nsizakalo ikhokhwa futhi ixhomeke ngokugcwele kwezifiso zomthengi.
Isampula segazi lezintambo
Ukuze ukhethe amangqamuzana egazi egazi, lokho kuthathwa ngokushesha ngemuva kokuba usana lubonakale ekukhanyeni. Lena yindlela kuphela yokubathola. Ngemuva kokuzalwa komntwana, umbelethisi uyadlula intambo yomzimba, emva kwalokho inaliti ifakwe kwesinye semithanjeni yakhe futhi igazi liqoqwe esikhwameni esikhethekile. Inqubo ingapheli imizuzu engaphezu kwemi-3 futhi ayibuhlungu ngokuphelele ingane nomama wayo.
Ucingo aludingi i-anesthesia futhi lwenziwa ngaphandle kokuxhumana ngokomzimba nengane. Inqubo iphephile ngokuphelele. Ngesikhathi esifanayo, isampula legazi lezintambo singenziwa kokubili kokubeletha kwemvelo kanye nalabo abenziwa yi-cache. Isimo esibophezelayo yisibonakaliso sokuqala sesifiso sikamama ngokubhala.
I-Cord isitoreji segazi
Ukushisa kwegazi lomzimba kuvumela ukugcina izinto eziphilayo isikhathi eside. I-laboratory ithola iphakheji elinyathelisiwe elibekwe uphawu emva kwesampula, eliqukethe igazi ngokwayo kanye nesici esivimbela ukugcoba kwayo. Ngaphansi kwezimo eziyinyumba, abasizi be-laboratory bakhipha i-stem cell concentrate yi-centrifugation. Okusele - i-plasma - ifakwe ezinhlobonhlobo zezifo ezithathelwanayo namagciwane ngaphambi kokuthunyelwa ebhange legazi lezintambo. Isampula ihlolwe nge:
- I-AIDS;
- i-hepatitis;
- i-cytomegalovirus ;
- i-syphilis.
I-cryoprotectant ingezwa isampula okufanele ihlolwe - into evimbela ukubhujiswa kwamaseli ngaphansi kwethonya lokushisa okuphansi. Isampula ngayinye inikezwa inombolo eyingqayizivele, emva kwalokho ibekwa ebhange. Isitoreji senziwa nge-nitrogen enomsoco ekushiseni kwama-degree angu -196. Lona ibhange lama-stem cells. Ezikhethekile ekugcinweni kwegazi lomthambo wegazi, izikhungo zinokuhlangenwe nakho ekugcineni impahla yakho iminyaka engama-20.
Amabhange wamaseli ase-stem
I-stem cell bank ye-umbilical cord igazi emazweni ase-CIS ikhona cishe kuwo wonke amadolobha amakhulu. Izimo zokugcina esikhungweni ngasinye zingahluka, ngakho-ke kufanele uqale uthintane ngolwazi oluthe xaxa. Inkontileka iphetha ngesiguli, okubeka izindleko zokuhlinzeka ngezinsizakalo, isikhathi sokugcina. Izinsizakalo ezifanayo zinikezwa:
1. ERiphabhlikhi yaseBelarus:
- 9 Isibhedlela sase-City Clinic, iMinsk;
- GU Isikhungo SaseRepublican Scientific and Practical of Oncology yezingane, Hematology kanye Immunology, Minsk.
2. eRussia:
- I-Gemabank, eMoscow;
- I-Flora-Med, eMoscow;
- I-Povolzhsky Bank Yamaseli E-Hematopoietic, iSamara;
- LLC "Trans-Technologies", eSt. Petersburg.
3. E-Ukraine:
- Ibhange lase-Ukraine lama-stem cells, eKiev.
Kubiza malini ukugcina amangqamuzana amancane avela emthonjeni womlomo?
Efuna ukugcina amangqamuzana abalulekile ukuze kube nokwelashwa okuqhubekayo, isiguli sivame ukuba nesithakazelo sokuthi izindleko ze-umbilical cord blood cost. Amanani ayashintsha njalo, okwamanje asethwe ezingeni elilandelayo:
- E-Russian Federation: ucingo - 500-700 $, isitoreji - 150-200 $ ngonyaka ongu-1.
- E-Ukraine: ucingo - 450-600 $, isitoreji - 100-200 $ ngonyaka.
- E-Belarus: isivuno se-stem cell ngu-500-600 $, isitoreji singama-100-150 $ ngonyaka.
Ama-Stem Cell - Izinzuzo Neziqholo
Njalo ngonyaka, abantu abafuna ukubeka ama-biomaterials baqala ukukhula. Kodwa-ke, ayikho imibono engacacile ekusetshenzisweni kwezinhlaka ezinjalo. Amangqamuzana e-stem abantu angakwazi ukulungisa izicubu nezitho ezonakalisiwe. Kodwa-ke, inqubo yokuvuselelwa okungahoxiswa ingaholela ekukhuleni okuqinile, okukhulisa ingozi yokubunjwa kwe-tumor. Njengoba sinikezwe lesi sici, phakathi kwezici ezinhle zokusetshenziswa kwamaseli a-stem:
- ithuba lokubuyisela isakhiwo nemisebenzi yelungu elithintekile;
- inqubo esheshayo yezicubu zokuvuselelwa;
- ukwelashwa kwezifo ezingokwemvelo.
Izimo ezimbi ekusetshenzisweni kwama-stem cells:
- izindleko eziphezulu zokuqoqwa nokugcina impahla;
- ukungabi khona komthelela oqinisekisiwe kusuka kwesicelo;
- ingozi eyengeziwe yokuthuthukisa izicubu.