Ezifweni ezihlukahlukene egazini kukhona izinto ezinobuthi, izakhi zokuvuvukala, amaseli wegciwane kanye nezinye izakhiwo zomzimba. Ukuzisusa, i-plasmapheresis isetshenziselwa - inzuzo nenzuzo yokusebenzisa le ndlela ixoxwa njalo emphakathini wezokwelapha. Abanye ososayensi bagcizelela ukungabi nalutho kwalolu buchwepheshe, kanti abanye odokotela banikeza izingqinamba eziqinile ukuze ziphumelele.
Izindlela eziyinhloko zokwenza i-plasmapheresis yi-filtration (i-membrane) futhi inamandla (ibhukwana, i-centrifugation).
Izinzuzo kanye nokuqeda kwe-membrane plasmapheresis
Le nqubo yokwenza inqubo iqala ukuhlunga okuqhubekayo kwegazi kumadivayisi akhethekile - izihlungi ze-plasma. Nge-cathéter, efakwe ku-1 noma 2 emithanjeni yesiguli, igazi liyathathwa. Iqhutshwa ngezihlungi ze-membrane ezibopha i-plasma ngezidakamizwa kanye namanye amangqamuzana e-pathological. Igazi legazi elihlanzekile lixubene nesisombululo se-isotonic bese libuyela ngokushesha egazini legazi. I-plasma ehlungiwe iqoqwe esikhwameni esithile se-polyethylene futhi isusiwe.
Izinzuzo ze-membrane plasmapheresis:
- ukuphepha;
- ukugcinwa komsebenzi ojwayelekile ngokomzimba wenhliziyo ngesikhathi sonke sesiseshini;
- isivinini (inqubo ihlala cishe ihora);
- ukungabi khona kwemizwa engathandeki;
- Sebenzisa isisononi kuphela isisombonic (biocompatible) negazi lomuntu siqu.
Azikho ukwehluleka okuphawulekayo kwiplasmapheresis eyenziwe ngendlela efanele. Ezimweni ezingavamile, isiguli singase sibe nesimo sosizi, ukuphazamiseka okuncane kwamalungu , ubuthakathaka noma isicashu. Lezi zimpawu ziphela ngokushesha.
Izinzuzo kanye nokuziqhenya kwe-plasmapheresis yamathuluzi kanye ne-centrifugation
Indlela yokuvuthwa yale nqubo ihilela ukuqoqwa kwegazi, okuhlanjululwa yi-sedimentation ngezigxobo ze-anticoagulants (i-plasmapheresis ye-manual) noma i-centrifugation esiqandisini.
Inzuzo kuphela yale teknoloji ingumphumela ofanayo nendlela yokwakheka kwekhanda. Futhi ukungalungi kwamaplasmapheresis okunamandla kunkulu kakhulu:
- inqubo ithatha isikhathi eside;
- akunakwenzeka ukuhlanza ngokushesha umthamo omkhulu we-plasma;
- ngemuva kwesampuli segazi kuyadingeka ukwethula ama-substitute noma ama-donor izidakamizwa;
- kudinga izikhathi eziningi.
Kubalulekile ukuphawula ukuthi izinzuzo nezindleko zanoma yiluphi uhlobo oluthile lwe-plasmapheresis kumele zixoxisane nodokotela kuqala. Lena inqubo yokwelashwa eqinile eyenziwe phambi kwezinkomba ezicacile, hhayi nje indlela yokuhlanza igazi .