Iyini le nqubo yenqubo?
Ukutshalwa kwe-embryon yesikhathi eside kuyingxenye yenqubo ephakeme kakhulu futhi eyinkimbinkimbi edinga i-laboratory ekhethekile, enezixhobo ezibiza kakhulu. Kungenxa yalesi sici akuzona zonke izikhungo ezihilelekile ku-IVF nokuhlela ukukhulelwa kunikeza inqubo enjalo.
Le ndlela ihilela ukutshalwa kwemibungu ngaphambi kwesigaba se-blastocyst. Amasu asetshenziswe ngaphambilini aphakamisa ukufakelwa kombungu emzimbeni wesifazane esigabeni sokuhlukaniswa kwawo, isb. ezinsukwini ezingu-2-3. Leli qiniso lanciphisa kakhulu impumelelo ye- IVF kanti inqubo yokudluliselwa kombungu kwakudingeka iphindwe kaningi.
Ukuguqulwa ekutshalweni kwemibungu ku-vitro kuye kwaholela ekuthuthukeni kwezobuchwepheshe emkhakheni we-embryology, ngenxa yentuthuko ekhethekile emkhakheni wezokwelapha okuzala. Le ndlela, esetshenziselwa ekuholeni imitholampilo yokuzala emhlabeni, ihilela ukuxhumana okude nombungu wezindawo ezikhethekile (SICM / SIBM kanye no-Embryo Assist / Blast Assist).
Kuyafaneleka futhi ukuphawula ukuthi le nqubo ayikwazanga ukukhona ngaphandle kokusebenzisa idivayisi ekhethekile - incubator eminingi-gas. Kuyo ukuthi ama-zygote amaningana abekwe kanye nomphakathi wezakhi. Ngemuva kwezinsuku ezingu-4-6, ochwepheshe bakhipha i-blastocyst kusuka kule divayisi futhi bahlole ukusebenza kwayo. Ngokusho kwedatha yemininingwane, cishe kusuka kuma-60-70% amaqanda azaliswe ngesikhathi se-IVF, kungenzeka ukuba uthole imibungu evamile.
Yiziphi izinzuzo zokulima isikhathi eside emibungu?
Le ndlela ye-IVF ivumela, okokuqala, ukuthuthukisa ikhwalithi yokukhetha (ukukhethwa) futhi isebenzise imibungu kuphela enekhono eliphakeme elibizwa ngokuthi i-implantation yokufakelwa kabusha. Ngamazwi alula, ukusetshenziswa kwalendlela kwandisa kakhulu amathuba okukhulelwa emva kweVIV.
Ngaphezu kwalokho, phakathi kwezinye izinzuzo zokulinywa kwe-embryo yesikhathi eside zibizwa ngokuthi:
- ukunciphisa inani le-chromosomal engavamile emibhrishini efakwe esiteji se-blastocyst;
- le ndlela ingokwenyama ngokuqhathaniswa ne-embryo ukudlulisela kuze kube yizinsuku ezintathu;
- ekulimeni isikhathi eside kwanele ukubeka imibungu engu-1-2 emgodini wesibeletho, i-tk. amathuba okuhlanganiswa nokuthuthukiswa kwawo aphezulu kakhulu;
- ingozi yokuthuthukisa inkinga enjalo njengokukhulelwa kwe-ectopic iyanciphisa kakhulu.
Yiziphi izinkinga zale ndlela?
Ngemva kokuqonda ukuthi lokhu kutshalwa kwe-gametes nemibungu yesikhathi eside isikhathi eside, lapho etshele ngezinzuzo zale ndlela ye-IVF, kubalulekile ukuthi ungakhohlwa ukushiyeka kwalendlela.
Eyokuqala yalezi yiqiniso ukuthi akuwona wonke ama-embryo ahlwanyelwe akhulekela ku-blastocyst, ezimweni eziningi kuphela ama-50% azofinyelela kulesi sigaba sokuthuthukiswa. Njengoba kunikezwe lesi sici, le ndlela inokwenzeka kuphela uma ngosuku lwesithathu lwama-embryo ukulima, kuhlale okungenani 4. Ngenombolo ephansi, amathuba okuthola okungenani okuvamile, afinyelele esigabeni se-blastocyst, iphansi kakhulu.
Ukulimala kwesibili kungabizwa ngokuthi umzuzu wokuthi noma ngabe umbungu ufinyelela esiteji sentuthuko edingekayo ukufakelwa kabusha, lokhu akunikezi isiqinisekiso esingu-100% sokuthi ukufakelwa kuyophumelela futhi ukukhulelwa kuzofika.