Esinye sezimbangela ezivame kakhulu zokungabikho kwamantombazane, kanye nokuvinjelwa kwamathebhu we-fallopian kanye ne-endometriosis, ukungasebenzi kahle kwe-progesterone. I-progesterone i-hormone edingekayo ekukhulelwe kanye nenkambo evamile yokukhulelwa. Uma ngesizathu esithile akwanele emzimbeni wesifazane, izinga layo lingadliwa ngokuthatha izidakamizwa ze-hormonal - Dufaston noma i-Utrozhestan.
Dufaston nokukhulelwa
I-Duphaston i-analog eyenziwe ngobuciko ye-progesterone. I-molecule yezinto ezisebenzayo zalesi sidakamizwa kufana nokuhlelwa kwe-hormone yemvelo, futhi, ukungena emzimbeni, kufeza imisebenzi yayo. Ngakho-ke, isibonakaliso sokusetshenziswa kukaDufaston ukukhiqizwa kwe-hormone progesterone emzimbeni wesifazane.
Chaza lokhu kuntuleka kungaba ngosizo lwezivivinyo ezikhethekile ukutadisha iphrofayela ye-hormonal. Igazi ezingeni lika progesterone kufanele lithathwe esikhathini esithile somjikelezo wanyangazonke - phakathi phakathi kwe-ovulation kanye nokuya esikhathini esizayo. Uma lo mjikelezo ungavamile, kuphakanyiswa ukunikela ngegazi cishe, okungenani izikhathi ezimbili nekhasi lezinsuku ezimbalwa.
I-Dyufaston inqunywe udokotela ukuze abelethwe uma ukuntuleka kwe-progesterone kuqinisekiswa ngokwethembeka. Ubuye akhethe uhlelo olufanele lokunakekelwa kwesimo esithile. Uma uthatha u-Dufaston, umthamo wayo kufanele usatshalaliswe ngokulinganayo usuku lonke. Ungathembeli esibonelweni somuntu futhi wenze izidakamizwa zokuzivikela. Isilinganiso esingalungile singabangela imiphumela emibi empilweni yakho.
Njengomthetho, ukwamukelwa kwe-djufaston ekuhleleni kokukhulelwa kufanele kuhlale kungaphansi kwesigamu sonyaka. Kodwa noma ngabe ngabe ukhulelwe ngemuva kokuthola uDufaston, yeka ukuphuza wena ngokwakho awukwazi. Kumele uthintane nodokotela wakho masinyane bese umtshela ngokuqala kokukhulelwa. Uyolungisa umthamo ngokwesimo.
Ngesikhathi sokukhulelwa, ukwamukela kukaDufaston kunemigomo ehlukile. Isibonelo, ukunciphisa ithoni yesikhumba bese udala izimo ezikhululekile zokuthuthukiswa kwe-fetus, kanye nokwakhiwa kokukhulelwa okuvelele nokulungiswa kwezigulane ze-mammary ku-lactation. Ngokuvamile, iDyufaston inqunyelwe abesifazane abakhulelwe uma kwenzeka besongelwa ukukhulelwa kwesisu esikhathini sokuqala sokukhulelwa.
Isenzo sikaDufaston
I-Duphaston iyisidakamizwa esinomphumela we-progestagenic okhethiwe kwi-mucosa ye-uterine. Ngosizo lwaso, ukwakheka kwe-endometrium evamile yesikhala kanye nokuqala kwesigaba sokufihla ekupheleni kwe-endometrium kungenzeka. Lokhu kunciphisa ingozi ye-carcinogenesis ne-endometrial hyperplasia, ebonakala ngenxa yesenzo se-hormone estrogen.
I-Duphaston ayinayo i-anabolic, isrogenic, i-androgenic, i-thermogenic, noma i-corticoid. Isidakamizwa asinayo imiphumela emibi eyenziwa kwezinye ama-progestin okufakelwayo, njenge-cyproterone noma i-medroxyprogesterone. Imiphumela ye-dyufastone ekuvuthweni - isidakamizwa asivimbeli ukuvuthwa.
Izinkomba zokuthatha izidakamizwa:
- ukungabi nalutho ngemuva kokungasebenzi kahle;
- i-endometriosis;
- ukusongelwa kokukhipha isisu okungahambi kahle ngokuhluleka kwe-progestin;
- i-dysmenorrhea;
- isifo sangaphambili sendawo;
- ukuya esikhathini ngokungavamile.
Ngaphezu kwalokho, i-Dufaston ingasetshenziswa njenge-hormone replacement therapy uma abesifazane bethola ukuthi banezinkinga ngenxa yokuqeda kokubeletha noma kwemvelo esibelethweni esingaqondile.
Ukungahambisani nokusetshenziswa kweDufaston ukubekezelelana komuntu ngamunye kwe-dydrogesterone nezinye izingxenye zikaDufaston, kanye nama-syndromes e-Rotor noDabin-Johnson.