Uma une- cholesterol ephezulu egazini futhi kukhona isongo sesifo senhliziyo, ukusetshenziswa kwezidakamizwa ezikhethekile. Izitatimende zokunciphisa i-cholesterol zisetshenziselwa yonke indawo, futhi umphumela wale mithi uqinisekiswa kokubili ukucwaninga nokusebenza kwesikhathi eside.
Ingabe izidakamizwa ze-statin ziphephile ekunciphiseni i-cholesterol?
Ukunciphisa i-cholesterol egazini esetshenziswe izinhlobo ezimbili zezidakamizwa - izitembu namafibrate. Uhlelo lwezenzo zabo lufana ncamashi. Lezi zidakamizwa zivimbela ukuhlanganiswa kwama-enzyme okuphethwe ukukhiqizwa kwe-cholesterol ngesibindi. Ngakho, izinga labo legazi lingancishiswa ngama-50% futhi kwezinye izimo ngisho nangaphezulu. Njengoba kungekho sizathu sokungabaza ukusebenza kwezimiso zomthetho, ake sibheke ukuthi lezi mithi ziphephile nokuthi ngabe ukusetshenziswa kwazo kulungile.
Ukunciphisa amazinga e-cholesterol usebenzisa ama-statins kuboniswa ngala maqembu abantu ngabanye:
- iziguli zokuguga;
- abesifazane emva kokuqala kokuya esikhathini;
- abantu abaye bahlaselwa yinhliziyo ;
- iziguli ngemuva kokwenza noma yikuphi ukuhlinzwa enhliziyweni nezitsha ezinkulu
- labo abangazange basizwe ezinye izindlela zokuvamise uketshezi lwe-cholesterol (ukudla, ukulahlwa imikhuba emibi, njll).
Lezi yizimo lapho kungenakwenzeka kuphela ukufaka ama-statins, kodwa futhi kuyadingeka kakhulu. Kumele kuqashelwe ukuthi le mithi ayinayo impumelelo, ngakho-ke ngemuva kokuyeka ukudla, izinga le-cholesterol liyovuka futhi ezingeni lokuqala. Ngokuvamile, lezi zinto zingabhekwa njengokuphephile, imiphumela emibi yokuthatha izitembu akuyona ingozi enkulu empilweni.
Uhlu lwezidakamizwa ze-statin zokunciphisa i-cholesterol
Amagama esimiso sokunciphisa i-cholesterol angase ahluke, kodwa isimiso sesenzo kuzo zonke izidakamizwa sinye. Kuphela izinga labo lokuphumelela nokubekezelelana ngesineke kuphela. Nazi amathrendi angcono kakhulu wanamuhla wokunciphisa i-cholesterol:
- I-Rosuvastine;
- I-Atorvastatin;
- Simvastatin;
- I-Fluvastatin;
- Lovastatin.
Ukuphumelela kakhulu kwalezi zinto yi-rosuvastine. Ikuvumela ukuthi ukhiphe i-cholesterol nge-55% noma ngaphezulu. Noma kunjalo, kuningi okungahambisani nalo muthi. Okokuqala, ngeke isetshenziswe abesifazane ngaphambi kokuqala kokuya esikhathini, njengokungalingani kwe-hormonal eqinile.
I-Atorvastatin iphinde isebenzise ama-statins ukunciphisa i-cholesterol ngenomthelela oqinile, amazinga ayo angama-45% noma ngaphezulu. Kunemiphumela emibi lapha, i-atorvastatin iphephile kakhulu ngakho-ke inqunywe odokotela kaningi.
I-Lovastatin inokusebenza okuphansi futhi, kodwa, ivumela ukuba i-cholesterol encane ibe yi-25%.
Ngaphambi kokuqala ukwelashwa nama-statins, sincoma ukuthi uhlole nodokotela wakho ukuthi ngabe kunezinye izindlela ezingempela zokuthinta izinga lakho le-cholesterol. Lokhu kuyiqiniso ikakhulukazi ezigulini ezine-diabetes mellitus - ukwelashwa nama-statins kulesi sigaba sabantu akubonanga neze imiphumela emihle.
Ngemuva kokuthi unqume ukuthi uhlobo luni lwesimanje, olukufanele kakhulu kunabanye, ungaqhubeka nokuzikhethela izidakamizwa ngokwayo. Nazi imithi, equkethe i-atorvastatin:
- Atoris;
- Atomax;
- I-Tulip;
- Liprimar;
- I-Torquard.
I-Rosuvastine itholakele kumalungiselelo anjalo:
- Isiphambano;
- Akorta;
- I-Rosewood;
- I-Tevastor;
- I-Mertenil.
I-Levastatin yenza njengento esebenzayo emithini ye-Cardiostatin ne-Cholletar.
I-Simvastatin iyingxenye yamaphilisi:
- ISinquard;
- Symvor;
- I-Zocor;
- Vazilip;
- Ovenkor.
Qaphela ukuthi imiphumela emibi kakhulu emitholampilo yesimiso ukulala nokungaboni kahle. Uma unquma ukusebenzisa i-statin, udokotela kufanele akhethe into ethile esebenzayo, ehlola ngokucophelela ikhadi lakho nomlando wezokwelapha. Lokhu kunciphisa ingozi yezinkinga.