Ukulungiswa kokwelashwa kwe-Longidase kunikezwa ngendlela yokujola nge-intramuscularly noma ngaphansi kwesisu. Kuyingozi ukuthola ngqo emithanjeni yegazi.
Esikhathini sokuqala sokwakheka kwempilo kunomqondo ophezulu wokuthi emva kokuthola ukwelashwa okwenziwa ngokusetshenziswa kwale mithi, ama-spikes ayophela, i-edema izonyamalalala, futhi ama-hematomas azoqedwa. I-Longidase isiza abesifazane ukuthi bangakwazi ukungena ngenxa yokubambelela okwenzekayo futhi kuthuthukiswe ngenxa yezifo ezingaziwa noma ezingasetshenziselwa ukugula.
Inhloso nesenzo se-drug Longidase
Umthamo wezenzo zalo muthi ukhulu kakhulu. Ngaphandle kwezicelo ezichazwe ngenhla, futhi kunikezwe amacala alandelayo:
- ukwelashwa kwesifo sofuba;
- i-pneumofibrosis ;
- i-alveolitis;
- i-cystitis engapheli emaphakathi;
- ukungabi nalutho kwe-tubal-peritoneal;
- i-prostatitis engapheliyo neyesikhuthazayo;
- ngokulimala;
- emva kwezifo zesikhumba, emva kwalokho kunezibazi nezibazi - i-pyoderma nabanye;
- emva kokushisa nokuhlinzwa;
- isivumelwano sokuhlanganyela;
- nge-hematomas;
- nge-arthritis.
Ukulungiswa kwe-Longidase kuthuthukisa ukondleka kwezicubu ezilinakele. Umphumela omuhle wezidakamizwa ubonakala ngokusebenzisa umsebenzi we-hyaluronidase. Ukumelana kwe-cell permeability kunciphisa, ukugeleza kwe-flux intercellular kwanda, okuholela ekuthuthukiseni okuphawulekayo kwesikhumba sokuqina. Ngenxa yalokhu, amalunga athola ukuhamba okukhulu.
I-Longitude iyilungiselelo le-enzyme elikhuthaza ukuwohloka kwamaprotheni. Ngaphezu kwalokho, unezenzo ezinjalo:
- anti-inflammatory;
- i-immunomodulating;
- i-antioxidant;
- ukuhlaziya;
- i-antifibrotic;
- ukuxosha amakhemikhali;
- ibopha izinsimbi zezinsimbi ezinzima;
- kuphazamisa ukuvela kwezicubu ezilahlayo;
- ayivumeli ukuthuthukiswa kwezigameko;
- kugwema ukubunjwa kwamaphrotheni e-collagen;
- kwandisa igciwane lesandulela ngculazi .
Ochwepheshe baye bafakazela ukuthi lesi sidakamizwa cishe asiyona into enobuthi, asinayo izakhi ze-carcinogenic, izitho zomzimba. Amasosha omzimba kanye nesistimu yokuzala ayihlupheki.
Izifo ze-Longidase 3000
Ngabe ngayiphi indlela (ngaphansi komcibisholo noma nge-intravenously) ukuphatha imithi, udokotela uzozikhethela ngabanye, ngokuya ngobukhulu besifo, iminyaka yobudala kanye nezinye izinto ezibaluleke kakhulu. Njengomthetho, ukujova kwemithi ye-Longidaz kufakwe eduze kwesayithi lesi sifo sendawo kanye nomthamo we-3000 IU. Inkambo yokwelapha yimijovo engu-5-15 nekhasi lezinsuku ezingu-3 kuya kwezingu-10, ngokuya ngobukhulu besigaba sesifo. Phindela inkambo uma kunesidingo, ungaphinda ungaphinde ube khona ezinyangeni ezimbili kuya kwezintathu.
Ukulungiswa kukhiqizwa ngezigqoko ngendlela efana ne-powder eyomile. Ngaphambi kokuba unikeze imishanguzo ka Longidase, imishanguzo ihlanjululwa kwisisombululo se-Procaine, noma i-sodium chloride noma i-liquid ekhethekile yezijoka.
Imiphumela emibi kanye nokuphikisana kwemigodi ye-Lognidaz
Okokuqala, udinga ukwazi ukuthi i-Longuidazum ayikwazi ukuphathwa ngesikhathi esifanayo nezidakamizwa equkethe:
- i-furosemide;
- phenytoin;
- benzodiazepines;
- ama-antihistamine;
- isragens;
- i-cortisone.
Ukuqhathaniswa okufanayo yizinto ezinjalo:
- uneminyaka engaba ngu-12;
- isikhathi sokukhulelwa kanye ne-lactation;
- ukutholakala kwezicubu ezimbi.
- ukuhluleka kwezinso;
- i-pulmary hemorrhage.
Imiphumela emibi nge-Longidazoy ukushaya kungenzeka ezimweni ezilandelayo:
- ukungezwani kwezingxenye ezakha umuthi;
- ukuzwela okwezingxenye zomuthi.
Phakathi kwemiphumela emibi yilezi:
- ubuhlungu, ubomvu, ukuvuvukala endaweni yesidakamizwa;
- ukusabela okweqile (akuvamile).
Kuyaziwa ngokuhlangenwe nakho ukuthi yonke imiphumela emibi yanyamalala ngemuva kwezinsuku ezimbili kuya kwezintathu.
Kokuhluleka okumbalwa I-Longidazy ingabonakala ukuthi imishanguzo iyabuhlungu kakhulu, futhi izidakamizwa akuzona ezishibhile.