Ama-hormone e-glucocorticosteroid yingxenye ebaluleke kakhulu yemigomo yokwelashwa ekwelapheni izifo eziningi ezihambisana nezinqubo zokuvuvukala. Kubandakanya i-Dexamethasone - imijovo yalesi sidakamizwa iphumelela kakhulu futhi ngesikhathi esifanayo iphephile. Uma kuqhathaniswa namanye ama-glucocorticosteroids, le-agent idala imiphumela emincane kakhulu.
Izici zemithi yezijovo zemithi Dexamethasone
I-agent ye-hormone ecatshangelwe iveza imiphumela emithathu emqoka emzimbeni:
- anti-inflammatory;
- i-immunosuppressive;
- antiallergic.
Ngaphezu kwalokho, isixazululo seDexamethasone sinciphisa i-edema ye-membrane emangcwabeni yendlela yokuphefumula, okudingekayo ekwelapheni izinqubo zokuvimbela amabhroniki, futhi iyanciphisa i-viscosity yemfihlo eyimfihlakalo, yenza kube lula ukukhwehlela.
Yiziphi izijovo zeDexamethasone?
Okokuqala, isidakamizwa esethuliwe sisetshenziselwa ukwelashwa kwe-hormone yokuguqula izifo ze-endocrine:
- i-hypoplasia yokuzalwa yangempela ye-cortex adrenal;
- Isifo sika-Addison;
- ukwehluleka okukhulu kwe-cortex enamandla, kokubili okuyisisekelo nesekondari;
- i-acute ne-subacute thyroiditis;
- i-adrenogenital syndrome;
- i-tumor hypercalcemia;
- hypothyroidism.
Izinkomba ezisele zokusetshenziswa kwama-Dexamethasone:
Isimo esithuthumayo:
- i-postoperative;
- emva kokuthungatha;
- ukumpontshelwa kwegazi;
- i-cardiogenic;
- ukushisa;
- inobuthi.
2. I-pathology yesimiso sokuphefumula:
- isimo se-asthmatic;
- isifo sokuphefumula esithathelwanayo esithathelwanayo;
- i-sarcoidosis ;
- ukukhushulwa kwe-bronchitis engavamile;
- bronchospasm enzima;
- Isifo seLeffler;
- wasakaza isifo sofuba;
- i-berylliosis.
3. I-edema ye-Cerebral nge:
- i-craniocerebral trauma;
- i-hemorrhages;
- izicubu;
- i-encephalitis;
- imisebenzi ye-neurosurgical;
- ukulimala kwemisebe yamaphaphu;
- i-meningitis.
4. Izifo ze-Rheumatic:
- isifo senhliziyo esiyingozi;
- isifo samathambo ngesikhathi sokukhubeka;
- basakaza i-lupus erythematosus.
5. I-anemia:
- idiopathic;
- i-autoimmune;
- ukuzalwa;
- i-erythroblastopenia;
- i-hemolytic;
- i-hypoplastic.
6. Izifo zesimiso sokugaya ukudla:
- i-hepatitis;
- i-nephrotic syndrome;
- i-neonicecific ulcerative colitis.
7. Izinqubo ezivuthayo nokuvuvukala emalungwini nasemisipha:
- i-tenosynovitis;
- i-epicondylitis;
- i-arthritis;
- i-bursitis;
- i-osteochondrosis;
- i-styloidite;
- Isifo sikaBechterew;
- i-osteoarthritis;
- myositis.
8. Izifo zegazi:
- i-thrombocytopenia yesibili;
- i-lymphomas;
- i-lymphocytic leukemia;
- purpura idiopathic thrombocytopenic;
- i-leukemia;
- i-plasmacytoma;
- i-agranulocytosis.
9. I-pathologies ye-ophthalmic:
- i-keratitis;
- iris;
- i-conjunctivitis;
- i-blepharitis;
- iridocyclitis ;
- i-keratoconjunctivitis;
- isikhombisi
- ophthalmia ozwelayo;
- i-blepharoconjunctivitis;
- i-episcleritis;
- ukuvuvukala emva kokusebenza emehlweni.
10. Izakhiwo zesikhumba:
- i-redusid i-lupus erythematosus;
- i-keloids;
- granuloma annular;
- i-dermatosis enzima kakhulu.
Ama-injection kaDexamethasone nawo anqunyelwe izifo, izilonda zesistimu zezicubu ezixhumene nezifo ezinzima. Esikhathini esilandelayo, imithi ye-hormonal ihlangene ne-antibiotic.
Indlela yokufaka kahle i-Dexamethasone?
Ezimweni eziphuthumayo futhi ezinzima, ukujova okufakwe emzimbeni kwalesi sidakamizwa kunikwa umthamo we-4-20 mg (kuye ngokuthi isifo esivuliwe) kuze kube izikhathi ezine ngosuku. Umjovo kufanele wenziwe kancane kancane, okungenani iminithi elingu-1.
Uma isimo sempilo sinelisekile, isidakamizwa kufanele siphathwe ngendlela efana nesimo esifanayo.
Inkambo yokwelapha okunjalo yizinsuku ezingu-3-4, ukugcina umthamo emva kokuqeda ukukhushulwa - 0.2-9 mg amahora angu-24. Uma kudingeka ukwelashwa okwengeziwe, hamba kuDexamethasone ngendlela yamathebulethi.
Ngesinye isikhathi ama-intra-articular and interstitial injections anqunywe. Ezimweni ezinjalo, umthamo wansuku zonke wesidakamizwa se-hormone ngu-0.2-6 mg.
Ukungafani nemiphumela emibi ye-injection Dexamethasone
Izifo nezimo lapho isixazululo esichazwe khona singasetshenziselwa:
- i-glaucoma;
- izilonda ezithathelwanayo zezicubu namajoyini ngezikhathi ezithile;
- i-hypersensitivity;
- izifo ze-amoebic;
- ifomu elisebenzayo lesifo sofuba;
- uhlelo lwe-mycosis;
- izifo eziphuthumayo ze-ocululent ocular;
- isikhathi ngaphambi nangemva kokugoma.
Mayelana nemiphumela emibi, i-Dexamethasone, njengombuso, ibekezelela kahle. Ezimweni ezingavamile, kunezinkinga ezingekho eziyingozi ezivela ezinkambeni zomzimba ezilandelayo:
- ukugaya;
- isifo senhliziyo;
- i-endocrine;
- ukwesaba;
- i-musculoskeletal;
- i-immune.
Ngezinye izikhathi izikhumba kanye nezindlela zendawo zithathwa, i-calcium metabolism, ukucabanga kwamalungu athile omqondo kuphazamiseka.