I-alkaline phosphatase iyinkimbinkimbi ye-enzyme ephethe ukuthuthwa kwe-phosphorus emzimbeni. Izakhiwo ezifana nesakhiwo zisebenza kakhulu emkhatsini we-alkali, ngakho igama elithi "alkaline phosphatase".
Ukuvivinya igazi kwegazi kuhlanganisa ukuhlolwa kokunquma izinga le-alkaline phosphatase. Kwezinye izimo, isifundo sibonisa ukwanda kokuqukethwe kwe-enzyme. Ake sithole ukuthi kungani i-alkaline phosphatase inganda.
Izimbangela ze-alkaline phosphatase ephezulu
Egazini lomuntu onempilo u-alkaline phosphatase liqukethe ngamanani amancane. Ngokombono wezinto eziphilayo, isizathu sokuthi kungani i-alkaline phosphatase yanda izikhathi eziningana ukufa kwamangqamuzana amaningi emzimbeni. Ngenxa yalokho, ukunyuka kwe-enzyme evamile ezimweni eziningi kubonisa ukuthuthukiswa kwesifo. Lokhu kwandisa izinga le-alkaline phosphatase kulezi zifo ezilandelayo kanye nezimo zokugula:
- izinqubo zokuvuvukala nezicathulo esibindi (isifo sofuba, isibindi, umdlavuza, izilonda zesimungumzimba zesitho);
- ukuqhuma kwebhili ngenxa ye-cholestasis;
- Izilonda ezithathelwanayo zamathumbu, ezihambisana nesifo sohudo, nesifo sofuba esiswini;
- ukuphazamiseka kwengqondo emathanjeni amathambo, ngokuyinhloko umdlavuza kanye namathambo ayisithupha;
- ukwehluleka kwe-calcium ne-phosphorus emzimbeni;
- izifo ezihlobene nezinguquko phakathi kwe-phosphorus-calcium metabolism (hyperparathyroidism, rachitis);
- isifo sikashukela mellitus ;
- i-infarction ye-myocardial;
- ukwehluleka okunamandla nokuhlala njalo.
Kumele kuqashelwe ukuthi izifo ezibi kakhulu, kuhlanganise nomdlavuza wezitho zangaphakathi, ziholela ekwandeni kwe-alkaline phosphatase.
Kodwa hhayi njalo ukwanda kokuqukethwe kwe-enzyme kunemvelo. Ngakho-ke, i-alkaline phosphatase ikhuphuka kancane kwabesifazane abakhulelwe, isizathu siwukuthuthukiswa kwe-placenta emzimbeni wesifazane. Ukukhula okuqhubekayo ebuntwaneni nasekuseni, lapho amangqamuzana evuselelwa ngokukhethekile, kungesizathu sokuthi izingane ezinomqondo ovamile we-enzyme ziphindwe izikhathi ezingu-2-3 kunabantu abadala.
Izimbangela zemvelo, lapho i-alkaline phosphatase ikhuphuka ku-140 IU / l, ingaba:
- ukuphuma esikhathini sokuphuka kwabesifazane ;
- ukuvuselelwa kwezinqubo zamathambo ngesikhathi sokuphulukiswa kwezinhlanzi;
- ukululama ngemva kokuhlinzwa;
- ukwamukelwa kwezidakamizwa ze-hepatotoxic (ama-antibiotics, izitho zomzimba zomlomo).
Izici zokudlula izidakamizwa ukukhuluphala, indlela yokuphila ehlala phansi, nokubhema.
Ukwelapha nge-alkaline phosphatase ephakeme
Uma imbangela yezinguquko ezingeni lika-alkaline phosphatase ikhulelwe noma iphuka, bese uthatha noma yisiphi isenzo akudingekile, ngokuhamba kwesikhathi inkomba izobuyela emuva evamile.
Uma ukwelashwa kwezimo ze-pathological isimisiwe, lapho i-alkaline phosphatase ikhuphuka, ochwepheshe baqhubeka ngenxa yalokhu. Ukuze unqume ukuthi yini ebangela ukunyuka kokuqukethwe kwe-enzyme, kunconywa ukuba ufunde izifundo ezengeziwe, kufaka phakathi ukulinganisa izinga le-gamma-glutamyl transferase egazini, ukuhlola isimo sesibindi - ukuthola inani le-bilirubin ne-creatine kinase, njll. Ngemva kokuhlola imiphumela yezivivinyo, umelaphi angaqondisa isiguli emincane isazi, isibonelo, i-endocrinologist noma i-oncologist. Ungudokotela obalulekile ozokhetha ukwelashwa komuntu ngamunye.
Ukuze kulungiswe imingcele ye-alkaline phosphatase, imithi ingabekwa.
Ukunakwa sicela! Ukunyuka okukhulu kwezinga le-alkaline phosphatase ngesikhathi sokukhulelwa kuyisibonakaliso se-pathology, isibonakaliso se-alamu somonakalo kumaseli we-placenta.