Lapho ukwelashwa izifo ezibangelwa i-microbial Klebsiellae pneumoniae enomthelela, i-bacteriophage Klebsiella ehlanjululwa ngama-polyvalent ivame ukusetshenziswa. Lokhu kulungiselelwa kuyatholakala ngesimo sekhambi elimanzi, elinokusetshenziswa okuhlukahlukene. Njengoba umkhuba ubonisa, ukuphumelela kwalesi sidakamizwa kufana nokufana nama-antibiotic anamandla.
Iyiphi i-bacteriophage esusiwe i-Klebsiella pneumonia?
Isithako esiyinhloko sesisombululo yizigaba ze-bacteria, eziwumkhiqizo wokubola kwama-microorganisms. Lapho i-bacteriophage ingena amangqamuzana e-pathogenic, i-microbial lysis (ukuqubuka) kwenzeka, futhi ngenxa yalokho, bafa ngokushesha.
Njengomlondolozo ekukhiqizeni izidakamizwa ezisetshenziswe nge-quinazole. I-concentration yayo iphansi (ngaphakathi kuka-0.1 mg / ml) futhi ayithinti izindawo zokwelapha zesisombululo sezidakamizwa.
Izinkomba zokuqokwa kwe-bacteriophage ehlanzekile i-Klebsiella pneumonia
Isidakamizwa sisetshenziselwa ukuphatha izifo ezilandelayo:
- i-cholecystitis ;
- i-dysbiosis yamathumbu;
- i-gastroenterocolitis;
- i-pancreatitis;
- ukutheleleka kwe-urogenital;
- ukuxhaswa kanye namanxeba anegciwane;
- i-peritonitis;
- i-colpitis;
- izifo zokuhlinzwa;
- i-pyelonephritis;
- i-bartholinite;
- i-salpingo-oophoritis;
- i-endometritis;
- omphalitis;
- i-cystitis;
- i-pyoderma;
- i-rhinoscleroma;
- ozena;
- i-osteomyelitis;
- i-mastitis;
- ama-abscesses;
- i-sepsis .
Futhi i-bacteriophage klebsiella inconywa ngokumelene ne-systemic kanye ne-pathologies yasendaweni ekusebenzeni kwesifo sofuba okubangelwa yi-bacterium, kuhlanganise nezinkinga ze-nosocomial.
Imiyalelo yokusetshenziswa kwe-bacteriophage Klebsiella ehlanjululwe ngama-polyvalent
Isixazululo singasetshenziswa ngezindlela ezihlukahlukene, kuye ngokuthi isifo esibangelwa yi-microorganism.
Ukusebenza ngaphakathi ngaphakathi kwamathambo omuthi wamathumbu kuqukethe amahora amathathu ama-30 we-bacteriophage amaminithi angu-60 ngaphambi kokudla. Leli yizinsuku ezingu-7-15.
Nge-pyelonephritis ne-cystitis, isikhathi sokwelashwa kwesistimu yizinsuku ezingu-10-20, umthamo ufana. Kumelwe futhi ujobe ikhambi endaweni yangasese (20-50 ml) kanye ne-renal pelvis (5-7 ml) nge-nephro- noma cystostomy.
Ukwelapha ama-purulent, amanxeba okuphulukisa, ama-bandage, ukuchelela, izinhlelo zokusebenza kanye namanzi we-bacteriophage (okungenani kanye ngosuku) asetshenziswa. Ngemuva kokuvula i-abscess nokukhipha i-exudate, imithi igcwele isitshalo (inani lingaphansi kwevolumu ye-pus). Ngosizo lwamanzi, u-20-200 ml wezidakamizwa ulawulwa njalo amahora angu-24. Uma amanxeba avela ngenxa ye-osteomyelitis, umthamo ophakanyisiwe wokugeleza ungama-10-30 ml, futhi i-turundum ingasetshenziswa.
Ukwelashwa kwezifo ezivuthayo zesifo somzimba kuhilela ukuphathwa kwansukuzonke ka-5-10 ml wezidakamizwa esibelethweni nasesiswini (1 isikhathi ngosuku). Inkambo yokwelapha ihlala ezinsukwini ezingu-14-15.
Ngezifo eziphuthumayo ze-upper and lower infiratory tract, i-bacteriophage ithathwa ngaphakathi (isilinganiso kanye nendlela yokusebenzisa kufana nokuphathwa kwamathambo emathunjini emathunjini) kanye nesisombululo njengesisombululo
Ukuvuvukala okunamathumbu kwamathumbu kuvumela ukusetshenziswa kwe-bacteria. Ukwenza lokhu, 1 isikhathi ngosuku ubeka i-enema (40-50 ml yesidakamizwa). Ukwelashwa kwendawo kufanele kuhlanganiswe nemithi yangaphakathi (izikhathi ezimbili njalo ngamahora angu-24).
Naphezu kokungabikho kwemiphumela emibi, kanye nokuphikisana nokuqokwa kwemithi echazwe, kubalulekile ukuhlaziya ukuzwela kwamabhaktheriya kuso ngaphambi kokuyisebenzisa.