Izifo ze-Fungal (i-mycoses) - iqembu lama-pathologies asakazekile ahlobene nokutheleleka kwe-microflora yefungal ye-membrane enamaqanda, isikhumba, izipikili, amehlo, kanye nezicubu zezingaphakathi zangaphakathi. Ukwelashwa kwesilonda kwenziwa ngokusetshenziswa okuyimpoqo kwezidakamizwa ze-antimycotic, ezifaka amaphilisi e-Irunin.
Irunin - ukwakheka kwamathebulethi
Isidakamizwa i-Irunin sisekelwe ekufakweni kwezinto eziphilayo ezisebenzayo iracraczozole - i-deria de triazole. Lesi sithako esisebenzayo sinomthelela owenziwe nge-antitifungal ngokumelene nezinhlobo eziningi ze-microflora fungal, phakathi kwazo:
- imvubelo fungi (candida);
- i-dermatophytes (i-trichophyton, i-microsporia, i-epidermophyton);
- isikhunta isikhunta (cryptococci, aspergillus, blastomycetes, histoplasm, paracoccidia, sporotricks, cladosporia, njll).
Amathebulethi avela ku-fungus yase-Irunin, ngenxa yesenzo sesithako esisebenzayo, kusiza ukuvimba isikhunta se-pathogenic ezingxenyeni ezibalulekile zesakhiwo sabo, ukusekela ubuqotho begobolondo, i-ergosterol. Ngenxa yalokho, amangqamuzana amangqamuzana ayeka ukukhula futhi ahlukanise, kancane kancane afe. Ngakho inqubo yokubhubhisa-izifo ezithathelwanayo zomzimba womuntu isuswe, kungenzeka ukuthi ukuvuselelwa kwabo kudala.
I-Irunin - uhlelo lokusebenza
Amaphilisi e-irunin antifungal asetshenziselwa ukuhlola okunjalo:
- ukutheleleka kwefungal isikhumba;
- i-mycosis ye-mucosa yomlomo, amehlo;
- i-otomycosis (ukulimala emgodini wangaphandle wokuhlola);
- candidiasis ezitho zangasese;
- Ama-mycoses ayesimo sezulu;
- umonakalo we-nail we-fungal;
- ukutheleleka kohlobo lwe-fungal;
- cryptococcal meningitis;
- lichen ezinemibala.
Uma ukungenisa i-Irunin kusuka ekukhunjini kusheshe kugxilwe emaphethweni emathunjini, kungena egazini futhi kusakaze ngezicubu zomzimba. Kulesi simo, ukuthatha ithebhulethi ngokushesha ngemva kokudla okunomsoco, ungathola ukutholakala kwe-bioavailability ephakeme kakhulu nokubopha izidakamizwa zibe amaprotheni wegazi. Okuqukethwe okukhulu kunayo yonke into esebenzayo kutholakala ngezicubu eziqukethe i-keratin, kanye nesibindi, amaphaphu, izicubu zamathambo, imisipha yamathambo, njll.
Isilinganiso kanye nemvamisa yemithi inqunywa uhlobo nohlobo lomonakalo, uhlobo lwe-pathogen. Ubude benkambo yokwelapha buhlukile futhi bungaba phakathi kwezinsuku ezimbalwa (nge-candidiasis) ezinyangeni eziningana (ngomonakalo wamaphaphu, izipikili). Ngaphezu kwalokho, ezinye izinhlobo zokutheleleka kwe-fungal zidinga ukuqokwa kwezifundo eziphindaphindiwe zokuthatha lesi sidakamizwa.
I-Irunin ne-thrush
Ukuhlwitha, noma u-candidal vulvovaginitis , ingenye yezifo ezivame kakhulu lapho abesifazane beya kubafazi besifo somzimba. Izimpawu zesilonda yizi: ukushaya ngaphakathi kwesiswini, ukuvutha, ukushisa, ukukhishwa kwamakhadi amhlophe okuvela emzimbeni. Izimbangela eziyinhloko zokwelapha ziyancipha ekuzivikelweni kwe-immune nokuhlukunyezwa kwe-microflora emzimbeni. Izifo ezingapheli zivame ukubonakala ngokucindezela okwenzeka ezinsukwini ezimbalwa ngaphambi kokuqala kokuya esikhathini.
Ngendlela efanele ye-thrush yokuphathwa ngokushesha nangempumelelo ngaphandle kokubangela izinkinga. Kulesi simo, ngokuvamile ukuqeda i-candidiasis yalesi sikhungo esinqunyiwe i-Irunin (kufaka nefomu eliphindaphindiwe). Ukuze kutholakale umphumela omuhle kunazo zonke, ukusheshisa inqubo yokutakula futhi kunciphisa ukubonakaliswa okungajabulisayo, kunconywa ukuba kwenziwe ukwelashwa ngenkathi uthatha amaphilisi e-Irunine namaphilisi okuphatha ngomlomo. Ngamazinga amancane okulimala, kuvunyelwe ukuphathwa kuphela yihlobo lendawo lomuthi.
I-Irunin yokuphatha ubulili isetshenziswe kanye ngosuku ngosuku lwe-suppository, okungcono ngaphambi kokulala ebusuku. Ifomu lendawo yokulungiselela lidala ukugxilwa okudingekayo kokwelashwa kwesakhi esisebenzayo ezinhlotsheni ezithintekayo, kanti kungena emzimbeni wegazi. Kufanele kukhunjulwe ukuthi phakathi nesikhathi sokwelashwa kufanele ugweme oxhumana nabo abaseduze, futhi ukuvimbela ukuvuselelwa, ukwelashwa kanyekanye komlingani wezocansi kungadingeka.
Irunin kusuka ku-nail ukhunta
Ukushintsha ukuma nomthunzi we-nail, ukubukeka kwemivimbo noma amachashazi kuwo, ukukhishwa okuqinile - konke lokhu kuyizimpawu zesilonda sefungal of the plates. Naphezu kokuningi kokupheka kwabantu kanye nezidakamizwa zangaphandle zokwelashwa kwalesi sifo, ngosizo lwezindlela zokwelapha zendawo, umphumela ophikisayo kakhulu awufinyeleleki. Ochwepheshe kuleli cala batusa ukuba bachithe izifundo ezimbili zokwelapha ezimbili zokuthatha izidakamizwa ezenziwe ngama-antifungal, ngokuya ngokujula kokutheleleka. I-Irunin nalesi sifo ithatha 200 mg izikhathi ezingu-1-2 ngosuku. Ipuleti ethintekayo ye-nail ivame ukukhishwa ngokuhlinzwa.
Amaphilisi e-Irunin avela ku-nail ukhunta asiza kahle, uma ukwelashwa kuholwa yizincomo zonke zezokwelapha, ungaphuli umthamo onqunyiwe nemvamisa yokusetshenziswa kwemithi. Umphumela we-irunin therapy ithebhulethi ubonakala emva kokuqedwa kwenkambo, njengoba izipikili zibuyiselwa (esikhathini esithile emva kwezinyanga ezingu-6-9). Uma izipikili zilimaza emilenzeni ngenkathi yokwelashwa, ukwelashwa kwezicathulo kufanele kwenziwe.
I-Irunin - ukungqinelani
I-irunin imilenze yemvubelo ayikwazi ukusetshenziselwa amacala alandelayo:
- hypersensitivity kuya engxenyeni esebenzayo yomuthi noma izidakamizwa;
- ukukhulelwa (ikakhulukazi i-trimester yokuqala);
- isikhathi sokuncelisa;
- ukuhluleka kwenhliziyo, ezinye izifo zenhliziyo (kuphela ngaphansi kokulawulwa kwe-cardiologist).
Ezimweni lapho, ngokufana nokwelashwa kwe-fungal infection i-Irunin, kunesidingo sokuthatha ezinye imithi, kubalulekile ukukwazisa udokotela ngalokhu. Amaphilisi e-Irunin awahambisani nemithi ethile, isibonelo, nge:
- Rifampicin;
- Terfenadine;
- I-Misolastine;
- Quinidine;
- Simvastatin;
- I-Ergometrine;
- I-Methylergometrinin Ave.
I-Irunin - ezifanayo
Emakethe yemithi yokwelapha, kunezinhlobo eziningi zomuthi obhekene nombuzo, oqukethe izinto ezifanayo ezisebenzayo. Ake sibhale ezinye izifanisi zamathebulethi i-Irunin:
- Itrazole;
- I-Kanazol;
- I-Miconiol;
- I-Orunite;
- I-Itramikol;
- Rumikoz.
Irunin - imiphumela emibi
Imiphumela emibi i-Irunin ingabangela ukutholwa kwe-systic, futhi okusabalalisa kakhulu phakathi kwabo yilezi:
- ubuhlungu esiswini;
- izinkinga zesitoreji;
- ukungabi nesifiso sokudla;
- ubuhlungu ekhanda;
- ukuvuvukala;
- isicasuli;
- ukwehluleka komjikelezo wokuya esikhathini;
- ukuphuziza kwesikhumba;
- i-angioedema ;
- i-urticaria;
- itching;
- ushintsho lombala womchamo.