Uma umbhangqwana ufuna ngempela ingane, futhi owesifazane akakwazi ukukhulelwa ngokwemvelo isikhathi eside, umndeni uqala ukuzama izindlela zokufakelwa. Enye indlela enjalo i-ECO ICSI (ICSI). Lokhu kuhlanganiswa kwe-in vitro usebenzisa umjovo we-intracytoplasmic.
ECO plus ICSI - kuyini?
I-IVF insemination yokufakelwa yindlela lapho amaqanda kanye ne-spermatozoa kufakwa khona esitsheni esisodwa. Kule ndawo, ukukhulelwa kwenzeka ngendlela "yemvelo". Kodwa i-ECO yi-ICSI yenziwa ngokuhlukumeza okwehlukile nokungajwayelekile emadodeni. Kungenzeka nge-tadpole eyodwa ejwayelekile futhi ebonakalayo ephathekayo.
Ukuphendula umbuzo odumile mayelana nokuthi i-IVF IVF iyini, ukuthi inqubo ngokwayo iqhubeka kanjani, kufanele kuthiwa le nqubo isenziwa ngokuhlakanipha ngaphansi kwe-microscope. I-embryologist ithatha i-spermatozoon engu-1 futhi iyifake ngqo eqandeni ngosizo lwamathuluzi amancane akhethekile (inaliti nomsizi ophethe i-capillary). Le ndlela isisiza ukutshala zonke ama-oocyte atholakala ngesikhathi sokuvala.
I-ECO kanye ne-ICSI yinkambinkimbi enzima kakhulu edinga umsebenzi ocacile futhi osheshayo wochwepheshe. Le nqubo iqhutshwa ngaphansi kwenyuka kane. Ngalendlela, odokotela basebenzisa uhlelo olucacile lwe-micromanipulation lapho izinsimbi zomculo zihlanganiswa khona. Ngenjabulo, ikuvumela ukuba uhumushe ukunyakaza kwezandla zibe yinkimbinkimbi yokusebenza kwemishini.
ECO Statistics ICSI
Ngaphambi kokuvuma le nqubo, imibhangqwana eminingi inesithakazelo kumbuzo walokho ukusebenza kwe-IVF ECHO. Ngokwezibalo, izinga lokuzala lingaba li-30 ukuya ku-80%. Ukukhulelwa kuncike ezintweni ezihlukahlukene, okubaluleke kakhulu kuzo:
- Ikhwalithi yama-germ cells. Isibonelo, i-spermatozoon ekhethiwe ingase ibe nezici ezinhle kakhulu ngaphandle, kodwa iqukethe nokukhubazeka kwe-chromosomal. Ithinta umphumela we-IVF IVF nesakhiwo seqanda, ikakhulukazi ikhono layo lokuhlukanisa.
- Ubudala besifazane. Njalo eminyakeni emihlanu, ukunciphisa kakhulu impendulo ekugqugquzelweni kokufakelwa. Isibonelo, ngaphambi kweminyaka engama-30, ithuba lokukhulelwa kusuka kokuqala lingu-48%, kuya ku 35-40%, emva kweminyaka engu-45 - kuphela 20%.
- Iqoqo lofuzo labazali. Umjikelezo lapho kuqhutshwa khona ukuphawula kunika ithuba elincane lokukhulelwa okuphumelelayo.
- Ukulimala kwempahla yezinto eziphilayo ngesikhathi sokukhulelwa yi-ICSI.
- Impilo yowesifazane kanye namandla akhe okukhuthazelela ingane eqinile.
Ngaphambi kokuqala kwenkambiso, umama olindelekile kufanele avakashele isazi sezinkinga zezinzwa ezihlangenwe nakho, nobaba - kanye nezakhi zofuzo, ukuze bangadluliseli ingane. Noma kunjalo kuyodingeka ukuthi unikeze konke ukuhlaziywa, ukudlula noma kwenzeke ukuhlola okuyinkimbinkimbi, futhi uma kunesidingo, kanye nokwelashwa kumyeni nomfazi. Akekho udokotela onganikeza isiqinisekiso esingu-100% sokuthi emva kokusebenza kwe-ICSI iqanda liyokwenziwa ngokunembile.
Uma ukukhulelwa kungenzeki ngemva kokugqugquzela okulandelanayo, ukuphumelela kwemizamo elandelayo kungancishiswa kakhulu. Ngezinye izikhathi kunezimo lapho ukufakwa kokulindelwe isikhathi eside kuye kwavela kusukela ngesikhathi sesishiyagalolunye. Ezimweni ezingavamile, odokotela banikeza ezinye izindlela zokwelapha ukungabi nabantwana: i-donor spermatozoa, ama-ovules, imibungu noma umama wokubeletha .
Iyini inqubo ye-IVF IVF - isinyathelo ngesinyathelo?
Ngaphambi kokwenza lokhu kuvuselela, abazali abazayo kumele baqale balungiselele izilwane zabo. Inqubo ye-ECO IVF yenziwa ngezigaba:
- Ukukhuthazwa kwama-ovari ukukhiqiza ama-oocyte. Owesifazane imithi ebizwa ngokuthi i-hormone, okufanele ithathwe zingakapheli amasonto amabili. Phakathi nalesi sikhathi, odokotela baqaphe ukuthuthukiswa kwezintambo futhi balindele ukuvuthwa kwabo.
- I-egg isizinda senziwe ngokushukela nokugqunywa kwe-follicles. Bese bebekwa amahora amaningana kumaphakathi wezakhi kanye nama-oocyte atholakele. Le nqubo yenziwa ngokusebenzisa i-anesthesia yokudambisa.
- Ukulungiselela isidoda nokuhlukanisa isidoda esisebenzayo , esiqala ukungenakulinganiswa nge-microneedle (siphazamiseke umsila), bese siphumelela kuyo.
- Kudluliselwa. Ku-microprimer, iqanda liqhutshwa, khona-ke i-microneedle ihlatshwa imvilophu yayo iphinde ijowe kumuntu.
Zingaki amaqanda ahlanganisiwe angabonwa ngosuku olulandelayo, futhi emva kwezinsuku ezingu-3 ama-pre-embryos adluliselwa esibelethweni sokuthuthukiswa okuqhubekayo. Zinikezwa nge-catheter encane ngaphandle kokusetshenziswa kwe-anesthesia. Ochwepheshe bakhetha imibungu ephakeme kunazo zonke, kanti ezinye zitholile futhi zigcinwe ukuze zisetshenziswe esikhathini esizayo uma ukukhulelwa kungenzeki.
Ukuqeqeshwa kwe-ECO ICSI
Ukuze kutholakale umphumela omkhulu, odokotela batusa ukuqhuba IVF nge-ICSI emjikelezweni wemvelo. Ngaphambi kokuqala kwenqubo, abazali besikhathi esizayo kufanele bahole indlela yokuphila enempilo, ukuzivocavoca, badle kahle futhi bayeke imikhuba emibi. Futhi, ochwepheshe batusa ukuhlolwa koku:
- I-HIV;
- Rh factor kanye neqembu legazi;
- Ukusabela kukaWasserman;
- i-hepatitis;
- i-spermogram;
- I-STI;
- ECG;
- ukuhambisana, njll
Iyini i-ICSI ene-IVF?
Inqubo ye-IVF IVF inikezwa kula macala alandelayo:
- Inombolo ephumayo yamaqanda ingaphansi kuka-4.
- Inani le-spermatozoa yeselula liphansi.
- Esigodini, ama-antisperm antibodies noma pathologies atholakale.
- I-spermatozoa yatholakala ngokusebenzisa indlela yokuhlinzeka epididymis ngesikhumba.
- Amaphesenti aphansi okuqala kokukhulelwa kwe-IVF.
Zingaki emibungu ezitshalwe nge-ECO IVF?
Izitebhisi ze-IVF IVF zihlanganisa ukubekwa kombungu we-embryo esibelethweni sowesifazane. Ochwepheshe bakhetha kubo okuhle kunazo zonke izicucu ezingu-2-3. Ngokuvamile imbungu eyodwa kuphela ifakwe, kodwa kunezimo lapho kungukuthi. Ezimweni ezinjalo, kwenzeka ukukhulelwa okuphindaphindiwe, okuqhubeka nokukhulelwa okujwayelekile. Kulokhu, umama olindelekile kufanele athathe inani eliphakeme leProgesterone.
Ukukhulelwa emva kweVIV IVF
Ukuthuthukiswa okugcwele kombungu, lapho ukukhulelwa kuka-ECO IKI kufika, mhlawumbe ngo-90%. Le nqubo idlulisela amathuba okukhuthazelela ingane enempilo, kodwa le ndlela ayinalo ngokwemvelo ukhethe amaseli wesondo. Ngenxa yalesi sizathu, umntwana unesifo somzimba esibhedlela. Ukuze lokhu kwenzeke ngaphambi kokukhulelwa, kuyadingeka ukuvakashela isikhungo sofuzo.
I-ECO ICSI - imfucumfucu
Ngenxa yobuchwepheshe besimanje, cishe wonke owesifazane angakhulelwa namuhla. Ekuhlaseleni kokukhulelwa emva kwe-IVF IVF okokuqala kuthinteka kokubili izici zemvelo zemvelo, kanye neziqu zomchwepheshe kanye nempilo yabazali. Khetha umtholampilo oqinisekisiwe, uhambelane nokuncoma odokotela, ukholelwa emphumela omuhle bese uyothola ngempela.