Amaphilisi e-Siofor ayiyisidakamizwa esakhiwe esenzelwe iziguli ezine- diabetes mellitus . Kungenxa yeqembu elikhulu lemithi ye-biguanide. Ukusebenzisa imithi yayo yanamuhla akufundile nje kuphela ukwelashwa, kodwa futhi nokulahla isisindo esiningi.
Ukwakhiwa kwamathebulethi Siofor
Isekelwe ku-metformin. Lesi sitho sisebenza kwi-glycogen synthetase, eshukumisa ukuqaliswa kwe-intracellular glycogen exchange. Ngenxa yalokho, amandla okuthutha ama-proteine we-glucose akhula kakhulu, inani le-cholesterol liyancipha, kanti ukukhululeka kwe-fatabolism kujwayelekile.
Phakathi kwama-tablet emaphilisi avela kushukela daiobet Siofor kukhona izinto ezifana nalezi:
- i-povidone;
- i-titanium dioxide;
- i-macrogol;
- i-magnesium stearate;
- i-hypromellose.
Isicelo seSiofor
Ngenxa yokuphuza imithi, ukukhula kwe-basal ne-postprandial glucose kwanda. Ngenxa yalesi sakhiwo, amaphilisi aseSiofor nawo athathwe nohlobo lwesibili lwesifo sikashukela. Okokuqala, lesi sidakamizwa sinqunyelwe iziguli ezinesisindo esiningi, ezingenakwelashwa ngokudla noma ezemidlalo.
I-Siofor isiza ukunciphisa inani le-glucose elikhiqizwa futhi likhulise ukuzwela kwemisipha ekwenzeni i-insulini, ukuze ushukela lususwe masinyane emzimbeni.
Thatha amaphilisi e-Siofor ohlobo lwe-2 wesifo sikashukela angasetshenziswa njenge-monotherapy, futhi ahlanganiswe nezinye izidakamizwa. Umthamo wokuqala uvame ukuba ngu 500 mg kabili ngosuku noma 850 mg kanye.
Ukungahambisani nokusetshenziswa kweSiofor
Awukwazi ukuphuza izingane zeSiofor kuze kube yilapho uneminyaka eyishumi, kanye nalabo abahlupheka ngenxa yokwanda komzwelo we-metformin nezinye izingxenye zamaphilisi. Ngaphezu kwalokho, lo muthi uphikisana uma:
- ukukhulelwa;
- ukwehluleka kwenqunu ;
- ukungakwazi ukusebenza kahle;
- izifo eziyingozi, okuholela ku-hypoxia wezicubu.