MAO inhibitors

I-MAO inhibitors yinto ephilayo esebenzayo eyenza ukwandiswa kwezimo zesisindo. Lezi zidakamizwa zihloswe ukwelapha izifo ezithile zesifo, ukucindezeleka, isifo se-narcolepsy nesifo sikaParkinson .

I-MAO inhibitors - ithinta ngani?

Ngezindawo zabo zokwelapha, lezi zidakamizwa zihlukaniswe zibe izinhlobo eziningana:

1. Ama-inhibitors angenakukhetha angenakukhetha, afana kakhulu nokubunjwa kuya kuma-iproniazides. Banciphisa inani lokuhlaselwa kwe-angina, futhi baholele umuntu ekucindezelekeni.
2. Izinqubo ezikhethiwe ezihloswe zihlose ukuqeda ukuhlanzwa kwe-noradrenaline kanye ne-serotonin. Lezi zidakamizwa zinomthelela wokucindezeleka.
3. Izidakamizwa ezikhethiwe ezikhethiwe zisetshenziselwa ukwelapha isifo sikaParkinson. Zihileleke ngokuqondile ekusetshenzisweni kwe-catecholamines ne-dopamine.

I-MAO inhibitors - uhlu lwezidakamizwa

Izidakamizwa ezingenakukhethwa

1. Ipronizade. Umuthi ovela eqenjini lama-anti-depressants. Unomphumela ocacile we-hepatotoxic - ulimaza isibindi somuntu.
2. I-Nialamide. Lokhu kuyinkinga yokucindezeleka. I-powder enhle yombala omhlophe nge-tinge ephuzi kancane. Awuhlanjululwa kahle emanzini, futhi ophuzweni - nakakhulu nakakhulu. Umuthi uvinjelwe abantu abanesibindi, izinso, izinkinga zenhliziyo. Kuyinto engathandeki ukusetshenziselwa abantu abanokukhubazeka kokusakaza kwe-cerebral.
3. Isocarboxazide. Kuvame ukusetshenziselwa ukuphatha ukucindezeleka nokuhlukunyezwa. Njengeminye imithi iqembu lingalimaza isibindi, izinso nenhliziyo.
4. Fenelzin. Kuthathwa ukuze kuthuthukiswe isimo jikelele. It is ikakhulukazi esetshenziswa njengendlela anti-depressant.
5. I-Tranylcypromine. Le mithi yenzelwe ukubhekana nokucindezeleka. Kubhekwa njengokuvuselela. Esigabeni esisebenzayo, i-agent ihamba kancane ibe i-amphetamine. Ezinye iziguli zingase zithembele kumphumela oshukumisayo.

Uhlu lwezidakamizwa ezikhethiwe ezikhethiwe-MAO inhibitors

1. Bethol. Kucatshangwa ukuthi i-anti-depressant. Inesenzo sokulwa ne-antireserpine. Umphumela we-potential of phenamine unikezwa.
2. MacLobemide. Ikhambi eliphathelene nezidakamizwa zokucindezeleka. Ukubunjwa kwalo kufana ne-befol, kodwa kusekhona umehluko esimisweni se-molecular. Ngesikhathi sokwamukela, izitho zangasese ezinomile, ubuhlungu ekhanda, isicanucanu, ukulala, noma okungahle kwenzeke. Kwesinye isikhathi izimo zokuqothulwa, izinkinga zesisu, ukuphazamiseka kwemisipha nokukhubazeka okwesikhashana okubonwayo kwaqashelwa. Iziguli ezinezinkinga zokucindezeleka kwe-bipolar zazivame ukushintsha ushintsho ku-mania.
3. I-Pyrazidol. Isenzo saso sifana ne-Inkazan neTetrindol. I-agent esebenzayo kubantu abanokucindezeleka okungenandaba. Unomphumela wokwehlisa. Ithuthukisa imisebenzi yokucabangela. Kuvela phakathi kwabanye ngenxa yokuthi kungenzeka ukulawula ithonya ohlelweni lwezinzwa.
4. Inkazan. Ubuye abe metralindol. Kubhekwa njengokulungiswa kwangempela. Lisetshenziswa ekuthuthukiseni i-schizophrenia, i-psychoic psychosis noma yokwelashwa kwezifo ezicathulo zobuchopho. Kuboniswa ukudonsa okunamandla nokuhleleka, ukuvinjelwa, nemibandela enezimpawu ezingalungile ze-hypochondriacal. Kuvame ukusetshenziselwa ukuphatha izimo ezicindezelayo ezigulini ezidakwa ngokweqile.

Yiziphi izidakamizwa ezihlukaniswa njenge-MAO inhibitors ezingenakuphikiswa?

1. Selegiline. Isidakamizwa, isenzo sakhe esibhekiswe ekwelapheni kwesifo sikaParkinson kanye nezidakamizwa ze-syndromes, okubangelwa ukungabi khona kwe-dopamine.
2. Razagilin. Lo muthi ungokwesizukulwane esisha sezidakamizwa. Ilwa ne-Parkinsonism ephawulekayo, ikakhulukazi ngezinsizakalo ezincane zemishini. Kuvame ukusetshenziselwa nezinye izidakamizwa zeqembu.