I-Oxytocin yokukhipha isisu

I-Oxytocin iyisilungiselelo se-hormone yokwenziwa komzimba futhi ifana nesakhiwo nesenzo se-hormone yesintu efanayo. Isenzo salo emzimbeni sincishiswe ekukhuthazeni imisipha ebushelelezi, okuyiyo eyenza izimbangela ze-uterine. Ngenxa yalesi sakhiwo, i-oxytocin isetshenziselwa kakhulu ekuguleni komzimba. Ngokuyinhloko, i-analogue yokwelapha ye-hormone oxytocin yemvelo isetshenziselwa ukukhipha isisu.

Ukungena emzimbeni wesifazane okhulelwe, i-oxytocin ingabangela ukukhulelwa kwesisu, okudala ukuphazamiseka. Ngokukhipha isisu, lesi sidakamizwa sisetshenziswe ikakhulukazi ezinyathelweni zakuqala zokukhulelwa. Nakuba le ndlela ingenye indlela ehlukumezayo ekuqedeni kokukhulelwa kokuhlinzwa, kuyingozi ukutholakala okungenzeka kokuphuma kwegazi. Ngakho-ke, i-oxytocin isetshenziswa njengendlela yokukhipha isisu, kanti umbungu usayizibukhulu obuncane futhi awusakabi nesikhathi sokunamathela ngokuqinile odongeni lwesibeletho.

Ukusetshenziswa kwe-oxytocin ekukhutheni

Kodwa kunezimo lapho ukusetshenziswa kwalo kudingekile emibhalweni engathí sina, ngokwesibonelo, uma kwenzeka ukukhulelwa okweqhwa kumakhomitha wesibili nowesithathu. Ukukhipha isisu kuleso simo kungaba nzima, kungadingeka ukuthi usebenzise ukubhujiswa kwe-intrauterine ye-fetus ngosizo lwezinsimbi, noma ukwenza ingxenye yocala, futhi ukwethulwa kwe-oxytocin, empeleni kubangela ukubeletha. Noma kunjalo i-oxytocin isetshenziselwa izimo zokuphelelwa kwesisu okungaphelele ukusiza lesi sibeletho ukuba sizihlanze izinsalela ze-embryo efile kanye ne-endometrium. Ukugqugquzela ngokucophelela kwemisipha ebushelelezi kubangelwa hhayi kuphela ezimweni ezidinga ukuqedwa kokukhulelwa, kodwa futhi ekuzalweni ngezigaba zayo. Ngakho i-oxytocin isetshenziselwa ukukhulelwa emasontweni angu-41-43, lapho ukuzalwa kungenzeki ngokwemvelo, futhi ingane ebusisiwe iqala ukuhlushwa yi-hypoxia. Le hormone isetshenziselwa ukwandisa umsebenzi emisebenzini emincane, okunciphisa isikhathi sokubeletha.

Oxytocin, njengendlela yokwelashwa

Kubuye kudingeke ukusebenzisa i-oxytocin ekuhlukaneni okungenakulinganiswa kwe-endometrium ngemuva kwesisu sokukhipha isisu sangaphambilini noma isigaba sokudla.

Ngezikhathi eziningi noma ukuphuma kwegazi, i-oxytocin inqunyiwe ekwelapheni okuyinkimbinkimbi ngegazi lokubuyisela izindlela. Kanye nazo zonke ezingenhla, kunezimo lapho i-oxytocin isetshenziselwa izinqubo eziqhubekayo ezigulini ezincelisayo. Ukwethulwa kwalo emzimbeni wesifazane onesihlengikazi kubangela ukuphuma kobisi.

Ukungafani kokusetshenziswa kwe-oxytocin

Ukungafani kokusetshenziswa kwe-oxytocin yilokhu:

• isikhundla esingalungile se-fetus esibelethweni (oblique noma esinqamulayo). Njengoba ukubeletha kwemvelo kungabonakali ngokuqoqwa kwengane kungenakwenzeka, ukuvuselela i-oxytocin kungabangela ukufa kwakhe, kubangele ukuqhuma okukhulu;
• i-placenta previa (kulokhu i-oxytocin ingabangela ukuphazamiseka kwamapayipi, ukuphuma kwegazi futhi, ngenxa yalokho, ukufa kwengane);
• ukutholakala kwesibindi esibelethweni (isibonelo, kusukela kwesigaba sangaphambilini sokugcina). Kulesi simo, amathuba okuphuka kwesibeletho ku-rumen mkhulu;
• i-pelvic encane yomzimba wesifazane ekubelethweni (ngokwalo, ukungafani phakathi kobukhulu bekhanda lesisu kanye nobukhulu bomkhonto womama ekubelethweni kungaholela ekulimaleni kokubili umama nengane);
• usongo lokuphuka kwesibeletho;
• iziqholo ezinamandla ze-uterine (esimweni sezingqinamba ezinzima, ukugqugquzela ngokweqile kungaholela ekukhuleni kwesibeletho).

Imiphumela ye-oxytocin

U-Oxytocin uvunyelwe ukusetshenziselwa kuphela esikhungweni sezokwelapha ngaphansi kokuqondiswa udokotela. Lokhu kuqapha kuyasebenza ngoba le hormone ingabangela ukugqugquzela okunamandla kwemisipha ebushelelezi, okungabangela isimo sokukhulelwa kwesibeletho futhi kubangele ukuvula ukuphuma.