I-Indomethacin iyi- drug non-steroidal anti-inflammatory and antirheumatic drug okusetshenziselwa ukusetshenziswa kwayo kunomthelela ekuqedeni ubuhlungu bezinkinga ezihlukahlukene, ukususwa kwezinqubo zokuvuvukala, nokunciphisa umkhuhlane ezindaweni ezivuthayo.
Ukufometha kwe-Indomethacin
Ukukhipha imithi ngendlela yamathebulethi (ama-dragees, ama-capsules), amafutha (i-gel), amaconsi eso, isisombululo somjovo kanye nama-suppository ama-rectal (suppositories). Ngokuvamile le mithi isetshenziswa ekwelapheni izifo ze-osteoarticular, ukuvuvukala kwamanye amalungu angaphakathi. Isithako esisebenzayo kuso i-indomethacin (i-indoleacetic acid derivative). Sifunda ukuthi yiziphi izifaniso ezitholakalayo zokulungiselela i-Indomethacin emakethe yezokwelapha.
Ama-analogues e-Indomethacin
Ama-analogues omakhiwo we-indomethacin kumathebulethi, isb. imishanguzo elinezici ezifanayo ezisebenzayo, yizidakamizwa ezilandelayo:
- I-Indoene;
- I-Indowis EU;
- Indocollar;
- Indotard;
- I-Metindole;
- I-Tridocin;
- Elmetacin, njll.
Lezi zifaniso ezifanayo ze-indomethacin zitholakala ngendlela yamafutha kanye nama-suppository. Kodwa kufanele kuqaphele ukuthi izidakamizwa ezibalwe zingase zihluke emthamo wezinto ezisebenzayo nakuloluhlu lwezingxenye ezengeziwe.
Uma imithi esekelwe i-indomethacin nganoma yisiphi isizathu ayinakusetshenziswa, ezinye izidakamizwa ezivela eqenjini lezidakamizwa ezingezona izidakamizwa eziphikisayo ezinemiphumela efanayo zingahle zinikezwe ukwelashwa. Isibonelo, izidakamizwa ezinjalo ziyi:
- Ketorolac;
- Ibuprofen;
- I-Naproxen;
- I-Nimesulide ;
- I-Piroxicam;
- Diclofenac nabanye.
Kumele kukhunjulwe ukuthi akusikiswanga ngokwayo, ngaphandle kokubonisana nodokotela ozofika, ukufaka esikhundleni sesidakamizwa esinqunyiwe nge-analogue noma ukuyisebenzisa kwenye ifomu, okungaholela ekuphenduleni okungalungile komzimba.