I-hormone yokukhula

I-hormone yokukhula (STH), njengoba ibizwa nangokuthi, i-hormone yokukhula, ingumzimba we-protein yemvelo eyenziwe ngokwenziwa kwe-pituitary gland. Umsebenzi oyinhloko owenziwe nguye ukugqugquzela ukukhula, futhi ngenxa yalokho - ukwanda kobukhulu bomzimba. Lokhu kutholakala ngokusebenzisa ukusebenza kwezinqubo ze-anabolic. Ukwengeza, le hormone yandisa umsebenzi wamafutha, ama-carbohydrate, kanye nemithi yamaminerali.

Yini enquma ukuhlanganiswa kwe-hormone yokukhula emzimbeni?

Kokubili inqubo ye-biosynthesis kanye nokufihla okulandelayo kwe-hormone yokukhula kuxhomeke emathonyeni ahlukahlukene ukuthi isimiso sezinzwa, ikakhulukazi izigungqimba zangaphakathi zokuvimba, sibe nomzimba. Yona kanye inqubo ye-synthesis ilawulwa yi-hypothalamus, ngokunembile nge-neurohormones yayo.

Umphumela we-STH emzimbeni wenziwa yi-insulin-like, izici zokukhula, futhi kuxhomeke kokubili inani nomsebenzi we-tissue receptors ye-hormone.

Ukunciphisa kanjani ekusithekeni kwe-STH emzimbeni?

I-hormone yokukhula evamile kakhulu inciphisa ebuntwaneni. Uma leli qiniso lingatholakali ngesikhathi futhi lingalungiswanga, njengoba selikhulile kakade, ukukhula kwalabo bantu akudluli ku-130-140 cm. Ngesikhathi esifanayo, ukwehla okuhambelana nobukhulu bezitho zangaphakathi kubonakala, okwaziwa ngemithi njenge-splanchnomycria. Kulezi ziguli, i-hormonal kanye nezifo ezibangelwa ukuxilonga umzimba nazo ziphawulwe. Ngakho-ke ukuvama kwesikhashana kuvame.

Kwenzekani emzimbeni ngokubambisana ngokweqile kwe-STH?

I-hormone yokukhula inganyuka emzimbeni phambi kwesifo se-pituitary semvelo yokukhiqiza ama-hormone. Ngesikhathi esifanayo, ngokuya ngesiteji lapho lesi sifo senzeke khona, ama-syndromes amabili emitholampilo ahlukile:

1. Ezinganeni, izinqubo zazo zokuqothulwa kwezidakamizwa ezingakapheli, kunyuke kakhulu ekukhuleni kwethambo, okuholela ekuthuthukiseni i-gigantism.
2. Uma lesi sifo senzeke kubantu abadala abaye baqedwa inqubo ye-ossification, kunyuke ekukhuleni kwethambo ngobubanzi, okuzoholela ekukhuleni komthambo wezincuba zomzimba. Ngenxa yalokho, kunwetshwa kwamathambo omzimba, kanye nokuyeka, ukuguqulwa kwamalungu, ukunyuka emakhaleni nasezindlebeni. Ngamanye amazwi, i-acromegaly iqala.

Ukwandiswa kwamazinga wegazi glucose egazini kungabangelwa nokuthatha imithi, ikakhulukazi, equkethe i-glucocorticoids neprogesterone.

Iyiphi izinga le-STH emzimbeni okufanele libe yinto evamile?

Izinga lokukhula kwe-hormone egazini lishintsha ngobudala. Ngesikhathi esifanayo, ukuxilongwa kokuqala kanye nokwelashwa okufika ngesikhathi, kubaluleke kakhulu ukulawula izinga lokumama kwe-hormone ezinganeni. Izinga layo lishintsha kanje:

• izingane 1-3 iminyaka: abafana (m) - 0.43-2.4 ng / ml; amantombazane (e) - 0.5-3.5;
• Iminyaka engu-4-6: m - 0,09-2,5; d - 0,1-2,2;
• Iminyaka engu-7-8: m - 0,15-3,2ng / ml; d - 0.16-5.4;
• Iminyaka engu-9-10: m - 0.09-1.95 ng / ml; i-0,08-3,1.

Uma usola ukuthi izingane ziphika, ukuhlaziywa kwenziwa ngezinga le-hormone yokukhula, imiphumela efaniswa nayo evamile. Kulolu cala, okokuqala qaphela iminyaka yengane.

Ngokuqondene nabantu abadala, isimiso saleli hormone egazini lifika ku-1.0 ng / ml. Kodwa-ke, ukuphakama kwesifo, ngokwesibonelo, ku-acromegaly, kufinyelela ekuhlungeni kuka-40-80 ng / ml. Ukwandiswa kwaleli hormone kule nqanaba nakho kuyinto ejwayelekile:

• i-gigantism;
• I-CRF (ukungaphumeleli kwengqimba engapheli );
• i-hyperglygic ;
• izicubu emaphashini, esiswini.

Ngakho-ke, lapho ingane ikhula ngemuva, okubaluleke kakhulu ekuxilongweni kwesikhatshana, kuyisimo se-hormone yokukhula.