I-Heparin iyisidakamizwa esiyi-anticoagulant yesenzo esiqondile, okungukuthi, ivimbela ukuvala igazi. Lesi sidakamizwa sikhiqizwa ngendlela yamafomu okusetshenziselwa kwangaphandle kanye noketshezi lwegazi. Kodwa ngokuvamile kuvame ukusebenzisa isixazululo seHeparin, njengoba iqala ukuphuthuma ukubunjwa kwe-fibrin.
Izinkomba zokusetshenziswa kwe-Heparin
Ngemva kokusungulwa kweHeparin, ukuhamba kwegazi ezintsheni kuvuliwe, ukujikeleza kwegazi kwe-cerebral kushintsha futhi isenzo se-enzyme ethile sinciphisa. Yingakho ngokuvamile lezi zijovo zisetshenziselwa ukuphatha nokuvimbela i-infarction ye-myocardial. Nika izidakamizwa ezinjalo ngamanani aphezulu futhi nge-embolism yamaphaphu.
Izimpawu zokusetshenziswa kweHeparin nazo ziyi:
- i-thrombosis ejulile ye-vein;
- angina pectoris;
- i-coronary artery thrombosis;
- i-arrhythmia;
- i-thrombophlebitis ;
- ukugeleza kwegazi okubi emangceleni;
- izinhlobo ezithile zokukhubazeka kwenhliziyo;
- lupus nephritis;
- i-glomerulonephritis;
- endocarditis yebhaktheriya.
Ngokwezinga elinciphile, lesi sidakamizwa sisetshenziselwa ukuvimbela i-thromboembolism enezinyosi kanye ne-DIC-syndrome yesigaba sokuqala.
Basebenzisa ama-injection we-Heparin kanye nokungenelela kokuhlinzwa, ukuze igazi legciwane lingasebenzi ngokushesha.
Indlela yokusebenzisa i-Heparin
Umphumela osheshayo kwenzeka ngemuva kokujova kwe-Heparin engaphakathi. Labo abaye baba nomjovo we-intramuscular ngeke bakwazi ukwenza kuze kube ngemva kwemizuzu eyishumi nanhlanu noma engamashumi amathathu, futhi uma umjovo wenziwa ngaphansi kwesikhumba, isinyathelo sikaHeparin sizoqala cishe cishe ihora.
Uma lo muthi unqunywe njengesilinganiso sokuvimbela, ngokuvamile ubeka injection engaphansi kwesisu ngamayunithi ayizinkulungwane ezinhlanu. Phakathi kwalezi zinxephezelo kufanele kube nezikhathi ezivela emahoreni angu-8 kuya kwangu-12. Akunqatshelwe ukusika i-Heparin ngaphansi kwesinye indawo endaweni efanayo.
Ukuze uthole ukwelashwa, ukulinganisa okuhlukile kwalesi sidakamizwa kusetshenziswa, okukhethwa udokotela kuye ngokuthi uhlobo luni nesifo sesifo kanye nezici eziqondene nomzimba wesiguli. Futhi ukuphatha izijovo zeHeparin esiswini, noma ukusebenzisa izidakamizwa nezinye imithi, kungenziwa kunqunywe ngaphandle kokuxwayiswa kukadokotela, ngoba i-anticoagulant enjalo ihambisana nemithi eminingi. Kodwa lapha ngesikhathi esifanayo ukusebenzisa i-Heparin namavithamini noma izithasiselo eziphilayo ezisebenzayo kungenzeka ngaphandle kokwesaba.
Ukunciphisa isisombululo sokusebenzisa izidakamizwa, ngoba asikwazi ukuxubana neminye imithi ngesirinji esisodwa. Izici zokusungulwa kwe-Heparin yukuthi ngemuva kokuphathwa kwe-intramuscular, ukwakheka kwe-hematomas, kanye nokuphathwa kakhudlwana ngale mithi, kungase kube nemiphumela emibi:
- ukusabela okweqile;
- ukugaya ukukhubazeka noma ukubambisana;
- ukwephulwa kokusabalalisa kwe-calcium;
- ubuhlungu obufana ne-migraine.
Ukungahambisani nokusetshenziswa kwe-Heparin
Ngokucophelela, i-Heparin kufanele isetshenziswe ngesikhathi sokukhulelwa nangesikhathi sokubeletha. Ngemuva kokuxoxisana nodokotela, ingabe le mithi ingasetshenziswa kulabo abahlukunyezwa ngokweqile.
Ungafaki i-Heparin emathunjini, nge-intravenously noma nge-intramuscularly, uma isiguli sichaza:
- isisu sesilonda;
- i-ulcerative colitis ;
- umsebenzi wesibindi okhubazekile;
- i-neoplasms emangalisa emaphethini okugaya;
- subac endocarditis yebhaktheriya;
- umsebenzi wokuqamba umonakalo;
- ukucindezeleka komzimba;
- isifo esiyingozi;
- ukucindezeleka kumuthi.
Futhi, ungasebenzisi lesi sidakamizwa kulabo abasandula ukuhlinzeka emehlweni, ubuchopho, isibindi noma i-prostate.