I-cirrhosis isifo esihambisana nesimo samangqamuzana enyama enempilo (i-hepatocytes) enezicubu ezinamafutha ezingakwazi ukwenza imisebenzi yazo. Ifomu elijwayelekile lesi sifo yi-cirrhosis ye-biliary, ebonakaliswa ngezindlela ezimbili - okuyisisekelo nesesibili. Zibonakaliswa izibonakaliso ezifanayo, kodwa izimbangela ezihlukahlukene zenzeke.
I-cirrhosis eyinhloko yebhiliyali yesibindi
Lesi sifo singokwemvelo futhi siqala ukuvuvukala okungapheli kwe-biliary tract (cholangitis), ngenxa yokuthi iyiphi i-cholestasis eqhubeka ngokuhamba kwesikhathi, okungukuthi, i-bile ngokuphelele noma iqede kancane ukungena kwi-duodenum. Le disorder ekugcineni iholela e-cirrhosis eyinhloko ye-biliary, izimpawu zazo zilandelayo:
- ukukhwabanisa isikhumba, ikakhulukazi ukuphazamisa ebusuku, okungahlala iminyaka eminingana;
- ubuthakathaka obukhulu emzimbeni;
- ubuhlungu ku-hypochondrium efanele;
- ukuthunjwa kwesikhumba emahlombe ehlombe, ukuguquguquka kwamajoyina, ngokuthuthukiswa kwesifo, isikhumba siba mnyama emzimbeni wonke;
- ipeni ekhulisiwe;
- ubuhlungu besisu;
- ukunambitheka okubabayo emlonyeni;
- ukudla okumbi;
- izinga lokushisa lomzimba elincane.
Iziguli eziningi kuze kube yilapho izigaba zokugcina zesifo zingakhathazeki. Ukuhlunga isikhumba kungaba yisizathu sokuvakashela kudematologist.
Ezikhathini zokugcina ze-cirrhosis, i-hydrocephalus ( ascites ) iqala.
Phakathi kweziguli ezine-cirrhosis yesibindi se-biliary, iningi labesifazane litholakala, kepha amadoda ahlupheka kaningi.
Ekuthuthukisweni kwesilonda sesibindi isisindo esibalulekile sidlalwe yizinto ezithathwa njengefa.
I-cirrhosis yebhilidi yesibili
Leli fomu liqala ngenxa yokuvinjelwa isikhathi eside (ukuvimbela) kwe-buct buct evamile, okubizwa nangokuthi i-cholechae. Izimbangela ze-disorder zibandakanya i-cholelithiasis nemisebenzi ehlobene yokuhlinzwa, kanye ne-pancreatitis engapheli kanye nama-neoplasms.
I-symptomatology ye-cirrhosis yesibili ye-biliary kanje:
- itching;
- ukuphuza okwesibhakabhaka nesikhumba (kukhula ngokushesha futhi ngokuqinile);
- shintsha ngombala wezinhlanzi (ukungcola kwazo);
- shintsha umbala womchamo ube mnyama omnyama;
- ubuhlungu ku-hypochondrium efanele;
- ukukhuliswa kwesipere .
Ngokuvamile, lezi zibonakaliso zenziwa nge-cholangitis ehlanganisiwe, ehambisana nokukhuphuka komshini wokushisa komzimba ukuze kufakwe izibalo, izikhukhula, ukujuluka.
Ngezigaba kamuva, okuthiwa. i-portal hypertension, okuyinto ukwanda kwengcindezi emgodini we-portal, kanye nesinye isibonakaliso sesibonakaliso se-cirrhosis - ukungasebenzi kahle kwe-hepatic-cell.
I-cirrhosis yesibili yesibindi yesibindi ivame ukuthinta amadoda aneminyaka engama-30-50.