Zonke iziguli ezinama-hypertensive ziyazi kahle ukuthi izidakamizwa zokunciphisa ukucindezelwa kwegazi zidinga ukuthathwa njalo, kuphela ngale ndlela umuntu angahlala kahle isikhathi eside. Sekungaphezu kweyishumi, i-Adelphan isetshenziselwe le njongo. Kodwa le mithi inezinkinga eziningi, okokuqala - ibangela isifo senhliziyo. Ake sithole ukuthi yiziphi izifaniso ze-Adelfan ekubunjweni azikho ukuphikisana okufanayo.
Ukwakhiwa kwe-Adelfan kanye nezinkinga eziyinhloko zomuthi
Imithi Adelfan ibhekisela ezindleleni eziyinkimbinkimbi ezilawula ukucindezelwa kwegazi. Futhi labo abanesakhiwo sokushintsha usuku lonke, lesi sidakamizwa asikhuthazwa. I-Adelphan ifaneleka kakhulu kwiziguli ezinesifo sofuba ngokunyuka okuncane njalo kwengcindezi, izimbangela zazo ezingasungulwa. Kulezo zimo lapho odokotela bekwazi ukubala isici esibangela ukushisa komfutho wegazi, izidakamizwa zezokwelapha ezithinta ngokuqondile ziyasetshenziswa. Kwezinye izimo, i-Adelphan isetshenziswa.
Into esebenzayo ejwayelekile ye-Adelfan iyinhlanhla. Le ngxenye ibhekisela kuma-sympatolics, okungukuthi, ama-reagents asithinta ingxenye ezwelayo yesistimu yezinzwa ezizimele. I-Reserpine yenza kancane ukuthunyiswa kwesifo somqondo ebuchosheni enhliziyweni, ngenxa yalokho inani lezinhlangothi zalo liyehla, ukushaywa kwegazi kuyanciphisa futhi igazi lihamba kancane kancane ngemikhumbi. Lokhu kubangela ukwehliswa kwengcindezi. Ingxenye yesibili yomuthi i-dihydralysin. I-myotropic spasmolytic, okungukuthi, into evuselela imisipha ebushelelezi yemithwalo yegazi, ikakhulukazi isifo esiphezulu. Ukunciphisa ukuqina kwemisipha kukhulisa izindonga zabo, kuba lula kakhulu futhi ukugeleza kwegazi kudlula kangcono.
Ngenxa yethonya eliyinkimbinkimbi ye-reserpine ne-dihydralysin, kungenzeka ukufezekisa ukunciphisa isikhathi eside emzimbeni wegazi. Kodwa lezi zinto zinama-contraindications amaningi:
- Isifo sikaParkinson ;
- isithuthwane;
- i-colitis;
- isisu sesilonda nesilonda se-duodenal;
- i-tachycardia, i-stenocardia ne-pre-infarction;
- i-anuria;
- ukulimala nokukhubazeka kwesibindi;
- ukukhulelwa kanye nokulahlwa;
- ukuzwela ezakhiweni ezisebenzayo ze-ejenti.
Futhi i-Adelfan therapy ayikwazi ukuhlanganiswa nokusetshenziswa kwama-inhibitors e-MAO, ukwelashwa kwe-electroconvulsive nokusetshenziswa kwemizwa yokuphumula. Zonke lezi zizathu ziyisizathu sokusesha omunye u-Adelphan, okungenzeka ukuthi abantu abanezifo bangasebenzisa ngaphandle kokusongela impilo.
Ukwakhiwa kwe-Adelfan-Ezidrex nezinzuzo zayo
I-analogue ephumelele kunazo zonke ye-Adelfan yi-Adelfan-Ezidreks yokwelapha. Iqukethe izingxenye eziyinhloko ze-Adelfan - i-reserpine ne-dihydralysin - kanye nesisindo esinciphisa imiphumela yaso emibi emzimbeni, i-hydrochlorothiazide. Lesi yisifo se-thiazide, esinciphisa ukubuyiselwa kabusha kwe-i-sodium ne-chlorine ions, okuthinta kahle imisebenzi exretory yezinso. Ngenxa yalokho, lesi sidakamizwa sisuswe ngokuphelele emzimbeni phakathi nosuku futhi asinaso isikhathi sokuthinta kabi izitho zangaphakathi, kubangele imiphumela emibi.
Izimpawu zokusetshenziswa kwalesi sidakamizwa zifana no-Adelphan, kodwa imiphumela emibi ingaphansi kakhulu. Lezi yizi:
- isifo sohudo;
- umlomo owomile ;
- i-anemia;
- ukugeleza kwegazi esikhumbeni sobuso;
- indigestion.
Ngokuvamile, izidakamizwa zibekezeleleke futhi zingasetshenziswa ekwelapheni abantu asebekhulile kanye nabantu abanezempilo embi. Ama-analogues amaningi aphumelelayo e-Adelfan-Ezidreks azange asungulwe kuze kube yimanje, lo muthi uyinguqulo yanamuhla ye-Adelfan engasasebenzi futhi isetshenziswa ngokugcwele ekwelapheni iziguli ezinomfutho wegazi ophakeme emhlabeni wonke.