Ngokuyinhloko, inani elikhulu labomama esikhathini esizayo ngesikhathi sokubeletha baphoqeleka ukuba basebenzise i-suppositories yama-rectal nge-indomethacin, ikakhulukazi ezinyathelweni zokuqala. Kulesi sihloko, sizokutshela ukuthi yiziphi izakhiwo zalesi sidakamizwa, nokuthi ngabe zingathathwa ngesikhathi sokukhulelwa.
Ngiyakwazi ukuthatha amakhandlela nge-indomethacin ngesikhathi sokukhulelwa?
Ezimweni eziningi kakhulu, amakhandlela ane-indomethacin anqunyelwe abesifazane abakhulelwe ngokunyuka kwezwi lesisu kanye nokukhipha isisu okuphazamisayo. Ngenxa yokuthi izidakamizwa zisetshenziswe ngokuqondile, zenza umphumela wayo ngokushesha futhi zisiza ukuvimbela ukuthuthukiswa kwezimo ezinzima.
Into esebenzayo yalesi sidakamizwa - i-indomethacin, - ibike izakhiwo zokulwa nokuvuvukala, i-analgesic, antipyretic ne-antiplatelet. Uma usebenzisa amakhandlela ngesisekelo salesi sigaba ngesikhathi sokubeletha kwengane, ukukhiqizwa kwe-prostaglandin, okuthinta izicubu zomzimba, kuvinjelwe emzimbeni wesifazane, ngenxa yalokho amathuba okukhulelwa kwesisu ayancipha kakhulu.
Nakuba izigciwane zezinsizwa zivame ukubeka lesi siluleko ezigulini zabo ezilindele ngenjabulo impilo entsha, eqinisweni, imiyalo yokusetshenziswa kwamakhandlela nge-indomethacin ibonisa ukuthi ayaphambene nokukhulelwa.
Akumangalisi ukuthi, ngoba into esebenzayo yalesi sidakamizwa ifinyelela emkhakheni we-placental futhi kwezinye izimo ingabangela ngisho nokufa kwengane engakazalwa esibelethweni. Ngaphezu kwalokho, ukusetshenziswa kwamakhandlela nge-indomethacin ngesikhathi sokukhulelwa kungaholela eminye imiphumela embi enganeni, okungukuthi: ukuhluleka ukumboza i-arterial duct ngesikhathi sokuqala kokuhamba kwesikhathi, noma, ngokuphambene nokuvalwa kwayo kwe-intrauterine, ukuphazamiseka kwamaplatelet amaningi, ukucindezeleka kwe-pulmonary, izinguquko ezishintshayo kule myocardium, emangcwabeni ye-intraventricular , ukwehluleka kwezintuthwane nokungasebenzi, izilonda ezihlukahlukene zendlela yokugaya nokunye okunjalo.
Yingakho kubalulekile ukuphatha lesi sidakamizwa ngokucophelela. Kodwa-ke, odokotela abaningi bayavuma ukuthi inzuzo okulindelekile yokusebenzisa i-indomethacin ekukhulelweni komama ozayo ngokungabikho kokuphikisana kunciphisa kakhulu amathuba okuba nengane esesiswini sikamama. Njengomthetho, ngokusho kwemithi kadokotela, abesifazane abalungiselela ukuzalwa komntwana, sebenzisa i-suppository engu-1 izikhathi ezingu-2-3 ngosuku kuze kube yilapho isimo sikhululiwe futhi izimpawu ezingathandeki zisuswe.