Abesifazane bavame ukuthola igama elithi "isigaba se-follicular" ezincwadini zezokwelapha bese babuza ukuthi kusho ukuthini.
Iyini isigaba se-follicular?
Leli yigama lesigaba sokuqala somjikelezo wokuya esikhathini ngaphambi kokuqala kokuvuthwa. Umjikelezo wonke wokuya esikhathini uhlukaniswe ngezigaba eziningana:
- isigaba se-follicular;
- isigaba sokuvuleka;
- isigaba sokuqamba .
Isigaba se-follicular siqala ngosuku lokuqala lokuya esikhathini, futhi siphela nge-ovulation. Isigaba se-ovulatory sihambelana nokukhululwa kwe-oocyte kusuka ku-follicle, futhi ngemva kokuba iqala isigaba sokuqapha.
Isigaba se-follicular sihlala isikhathi esingakanani?
Isigaba se-follicular sisuka ku-7 (esifushane) kuya ezinsukwini ezingu-22 (eside), ubude bayo buphakathi kwezinsuku ezingu-14. Phakathi nalesi sigaba, i-endometrium inqatshiwe futhi isikhathi sokuya esikhathini siqala. Khona-ke, ngaphansi kwesithonya se-horlicone-stimulating (i-FSH) ye-pituitary gland, ukukhula kwe-follicle kuqala ku-ovary.
Ku-follicle ekhula, i-estradiol ikhiqizwa, ngaphansi kwethonya lesigaba sokukhula kwe-endometrium esibelethweni kuqala. Ngokunyuka kokugxilongwa kwe-estradiol ku-follicle, i-inhibin B idedelwa ukukhulula izinga le-FSH nesilinganiso esiphezulu se-estradiol ekuqaleni kokuvuthwa.
Ezinsukwini eziyisihlanu zokuqala zesigaba, izintambo eziningana zikhula, lapho izingqimba eziningana zamangqamuzana azungeze i-oocyte kanye ne-follicular fluid zivela. Ngosuku lwesishiyagalolunye nesikhombisa sesigaba se-follicular, enye ye-follicles iba yilapho iqhubekela phambili, inqwaba abanye ekukhuleni, futhi kuyo ukuthi inani elikhulu kakhulu le-estradiol kanye ne-inhibin B lihlanganiswa. Ama-follicle angenayo eqalayo aqala ukuthuthukiswa okuphindaphindiwe nokuthuthukiswa kwawo. Kusukela kulo mzuzu nangaphambi kokuqala kwe-ovulation, inani le-follicular fluid kanye nezinga lama-hormone elikulo ukwanda, okunomphumela wokulibazisa emgodini we-pituitary. Ngakho, izinga le-FSH linciphisa, futhi lokhu kuvimbela ukukhula nokuvuthwa kwamanye ama-follicle.
Umthelela wesigaba se-follicular ku-endometrium
Izinguquko ezingeni le-estrogens ezintweni ze-follicles, nokwanda kokuqukethwe kwabo egazini, kunomthelela olawulayo ekukhuleni kwe-endometrium esibelethweni. Ngomqondo ophansi we-estrogen, isigaba se-desquamation (isisu sokuphuma esikhathini) siqala. Kodwa, ngokukhuphuka kokuqukethwe kwabo, ukuphuma kwegazi kuyayeka futhi isiqalo sokuvuselela siqala (ngesikhathi esifanayo nokukhula kobuciko) kanye nokwanda (ukukhula) kwe-endometrium esibelethweni (ngokuhambisana nokukhula kobuciko obukhulu ). Esigabeni sokuvuvukala, ngesikhathi iqanda lishiya i-follicle, i-endometrium yesibeletho isilungele ukunamathisela iqanda elifakwe umanyolo emgodini wesibeletho.