Isifo sikaSjogren sika-syndrome sibhekisela ezifweni ezithinta izifo ezithinta izicubu ezixhunyiwe zezingqungquthela zokufihla - ikakhulukazi zinyathele futhi zishaye.
Njengezinye izifo ezizimele, isifo sikaSjogren sinesimiso se-systemic. Kuyinto evame kakhulu phakathi kwalezi zifo ezithinta izicubu ezixhunyiwe.
Esigabeni sengozi yesifo, abesifazane basendaweni ekhethekile, abahlukunyezwa ngesifo sikaSjogren izikhathi ezingaphezu kuka-20 kunamadoda. Isici seminyaka kule nkinga ayinandaba - lesi sifo singenzeka esikhathini esukela eminyakeni engu-20 kuya kweyengu-60.
Izimbangela zesifo sikaSjogren
Namuhla, imithi ye-immunology ingenye yezindawo ezingavunyelwe kakhulu zemithi. Njengoba kunikezwa ukuthi yizinqubo ezizenzekelayo ezenza ukuthuthukiswa kwesifo se-Sjogren, odokotela abakwazi ukuphendula ngokungaqondile ukuthi yini eyabangela lesi sifo. Kuyaziwa ukuthi ama-T-lymphocytes nama-B-lymphocytes atholakalayo ezilonda zesisu ngesikhathi sokuhlolwa. Inani elikhulu le-immunoglobulins nalo liyabonakala. Lokhu kuphakamisa ukuthi i-T-superstressors incishisiwe, okusho ukuthi amaseli B avuliwe.
Ekuhlolweni kwamagundane, ososayensi bathola ukuthi imbangela yefa yokuthuthukiswa kwesifo sikaSjogren kungenzeka kakhulu.
Izimpawu zesifo sikaSjogren
Isifo sika-Sjogren singaba nenkambo engapheli, uma iqala - ithuthukiswe ngaphandle kwemfuneko evela kwezinye izifo. Kukhona nesifo sesibili sikaSjogren, futhi kulokhu kubangelwa inkambo ende yezifo - i-arthritis, i-lupus erythematosus, i-scleroderma, njll.
Isimpawu esiyinhloko salesi sifo kungumile wezinambuzane ezinamanzi. Njengoba kunikezwa ukuthi izigulane ezisezingeni eliphansi kanye nelecrimal ziyathinteka, odokotela bahlukanisa lezi zimpawu zibe izinhlobo ezimbili:
- i-xerophthalmia - okuthiwa "iso elomile", lapho amehlo ebonakalayo efakwe khona. Ukuvutha komsindo nesihlabathi;
- i-xerostomia - okuthiwa "umlomo owomile", okunciphisa ukwehla futhi kukhona stomatitis, caries, parotitis, "galling".
Njengoba lesi sifo siqala kancane kancane, singathinta nezinye izindawo zomzimba:
- isikhumba esomile;
- ukubunjwa kwe-crust ekhaleni;
- itching ngaphakathi kwesifazane;
- i-tracheobronchitis;
- i-atrophic gastritis, i-dyskinesia ye-biliary, i-pancreatitis;
- i-glomerulonephritis ;
- I-Raynaud's syndrome;
- i-neuritis ye- facial and trigeminal nerve.
Ngokuvamile, iziguli zizwa ukwehla ngokuvamile kwamandla, kanye nobuhlungu emisipha kanye namalungu.
Ukuxilongwa kwesifo sikaSjogren
Ukuze uhlolisise lesi sifo, udinga ukusebenzisa izindlela eziningana:
- iphrofayli emzimbeni we-antinuclear;
- Ukuhlola kukaSchirmer, okuvumela ukuhlola ukusebenza kwezingqungquthela ezilahlayo. Kulesi sifundo, umdwebo wephepha ubeka phezu kwejwabu leso elingaphansi, futhi emva kwesikhashana ubude bezingxenye ezimanzi ephepheni lilinganiswa;
- i-sialometry - le ndlela inquma ukuvalwa kwemathe nge-ascorbic acid;
- i-sialography - indlela esekelwe kwi-radiopaque, isiza ukuphenya igundane le-parotid salivary;
- ukuhlolwa kwamehlo ngesibani sokubamba;
- I-biopsy ye-lip igcizelela ukungena kwezingqimba zomzimba;
- I-US yezingqungquthela ezisezingeni eliphezulu ibuye ivumele ukuthi inqume isimo sezinhlayiya ezisezingeni eliphakeme kanye nokuba khona kwamatshe emidayeni.
Ukwelashwa kwesifo sikaSjogren
Namuhla, imithi ayinayo izindlela ezingasindisa umuntu esesifo sikaSjogren, ngakho-ke, ngokuyisisekelo, ukwelashwa kunciphisa ukunciphisa izimpawu.
Isibonelo, amehlo omile angaphansi kwengqondo asetshenziselwa izinyembezi zokufakelwa - lezi zingamaconsi angenambala, okwakhiwa okufana nomuntu. Futhi kufanele isetshenziswe izikhathi eziningana ngosuku ukuvimbela ukoma kwe-mucosa.
Ngokunqotshwa kwezingqungquthela zomzimba, odokotela banikeza izidakamizwa ezikhuthaza ukuphuma kwamathe - enye yale mithi ibizwa ngokuthi i-Pilocarpine.
I-Corticosteroids isetshenziselwa izimo ezimbi kakhulu uma izinkinga zifakazela ingozi yokuthatha le mithi.
Ukwelashwa kwesifo se-Sjogren ngamakhambi abantu
Amakhambi omphakathi nawo akwazi ukukhipha lesi sifo, futhi angabangela ukulimala umzimba.
Kunendlela eyodwa abanye abantu abayisebenzisayo ukuphulukisa isifo sikaSjogren - izijovo ngeqanda elikhukhuni lezinkukhu. Kuyadingeka ukuthi uhlaziye amagciwane amaqanda amasha enkukhu, bese uthatha cishe ama-cubes amathathu amaprotheni uphinde ululise nge-saline ngesamba esifanayo. Ingxube ifakwe engxenyeni ye-intramuscularly emathangeni 1 isikhathi ngesonto inyanga eyodwa. Le ndlela ingaba ingaphephile kakhulu ngenxa ye-salmonella.
Ngaphambi kokusebenzisa le ndlela, khumbula ukuthi ngaphandle kokuvunyelwa udokotela, ukuzivocavoca kungaholela ezifweni ezintsha.