Isifo sikaCrohn sibhekisela ezifweni zomuthi wamathumbu. Kubizwa nangokuthi kungapheli emathunjini e-ulcerative colitis, ngoba ikakhulu ukuvuvukala kwenzeka emathunjini.
Isimo sesifo siyinkimbinkimbi, futhi odokotela abaqapheli ngokugcwele izinqubo ezibangela isifo sikaCrohn. Kuhlotshaniswa nezinqubo ezizimele, okwamanje ezifundiswa ngokuzikhandla emithi.
Isikhathi sokuqala lesi sifo sachazwa yi-American gastroenterologist uBernard Krohn ngo-1932, okwakubangela isifo esingenakulonda esiswini esingamapilini futhi sanikwa igama lesibili.
I-Pathogenesis yesifo sikaCrohn
Namuhla, odokotela bachaza izinto ezintathu ezikhulisa kakhulu amathuba okuthuthukisa lesi sifo:
- i-genetic;
- i-infectious;
- immunological.
Ngakho-ke, okokuqala phakathi kwezimbangela ezibangelwa isifo sikaCrohn yisifo sezofuzo. Ososayensi balinganisela ukuthi ezigulini ezingu-17%, izihlobo zinezifo ezifanayo, futhi lokhu kusho ukuthi ithuba lokuthuthukisa isifo sikaCrohn liyakwanda ngenxa yobuhedengu. Futhi, isayensi iyazi ukuthi uma omunye wabazalwane ethola lesi sifo, kusho ukuthi kuzovela okwesibili.
Indima yesifo esithathelwanayo ayiqinisekisiwe namuhla, kodwa lokhu akuvimbeli ukucabanga ukuthi ukutheleleka kwegciwane noma ukwelashwa kukhuthaza ukuthuthukiswa kwesifo sikaCrohn (ikakhulukazi, amabhaktheriya e-pseudotuberculosis).
Iqiniso lokuthi izitho zika-Crohn's isifo sithinteka ngokusungula ososayensi ekucabangeni ukuthi lokhu kuhlasela kubangelwa izinqubo ze-autoimmune. Iziguli ezihlolwe zinezibalo ze-T-lymphocyte ezandisiwe, kanye nama-antibodies ku-E. coli. Kungenzeka ukuthi lokhu akusona imbangela yalesi sifo, kodwa umphumela womzabalazo wezinto eziphilayo nesifo.
Izimpawu zezifo zika Crohn kuBantu abadala
Izimpawu zesifo sikaCrohn zixhomeke ekuzileni kwesifo kanye nobude besifo. Iqiniso liwukuthi lesi sifo singathinta wonke umgudu wokugaya ukudla, kusukela emgodini womlomo futhi uphele ngamathumbu. Uma sicabangela ukuthi intombazane ivame ukuthinteka, izimpawu zingahlukaniswa zibe zivamile futhi zisemathunjini.
Izimpawu ezivamile zesifo sikaCrohn zihlanganisa:
- ubuthakathaka;
- ukukhathala;
- ukuphakama kokushisa.
Ukubonakaliswa kwamathumbu emzimbeni wesifo sikaCrohn:
- isifo sohudo;
- ubuhlungu, okwenza i-appendicitis;
- isicasuli;
- ukuhlanza;
- i-anorexia;
- ukulahlekelwa kwesisindo;
- ukubhoboza emathunjini.
Isifo sikaCrohn singathinta ezinye izitho nezinhlelo:
- izimpawu zeso - conjunctivitis, uveitis, keratitis;
- izimpawu ze-articular - i-anondlosing spondylitis, i-monoarthritis;
- Izimpawu zomlomo - stomatitis;
- izimpawu zesikhumba - angiitis, i-erythema;
- izimpawu ezibuhlungu - isibindi sokudla kwesibindi, i-cirrhosis;
- izimpawu ze-renal - i- cystitis , i-pyelonephritis, i-hydronephrosis, i-nephrolithiasis, i-amyloidosis yezinso.
Isifo sikaCrohn sihambisana nezinkinga ezilandelayo:
- ukubonakala kwe-fistula yangaphakathi, i- perforation ye-ulcer , i-peritonitis;
- ukuvuvukala okuholela ekunqandeni kwezicubu kungaholela ekusenikeni kwe-lumen futhi kubangele ukuvimbela emathunjini;
- ngenxa yezilonda, ukuphuma kwangaphakathi kungabonakaliswa;
- ngenxa ye-fistula, izitho zangaphakathi zingatheleleka nge-HIV - isisu, isisu.
Lezi zinkinga zihlinzeka ngemvelo futhi ziqedwa ngendlela efanele.
Ukuqeda kwesifo sikaCrohn kuphele isikhathi esingakanani?
Kuye ngesithombe somuntu ngamunye wesifo, ukutholakala kwezinkinga nokukwazi komzimba ukuvimbela ukuvuvukala, isifo sikaCrohn singahlala
Ukubikezelwa kwesifo sikaCrohn
Naphezu kweqiniso lokuthi ezimweni eziningi ukulinda kompilo kuvamile iziguli ezine-Crohn's disease, noma kunjalo, izinga lokufa kwalesi sigaba sabantu lidlula izinga eliphindwe izikhathi ezimbili ngokuqhathaniswa nesilinganiso esivamile.
Ukuxilongwa kwesifo sikaCrohn
Izindlela eziningana ezisetshenziselwa ukuxilonga isifo sikaCrohn:
- i-endoscopy;
- ukuhlolwa kwegazi;
- I-X-ray;
- I-Ultrasound;
- ikhompyutha ye-tomography.