Impendulo eyinhloko cishe cishe yonke i-diuretics esebenzayo (i-diuretics) yi-excretion ye-potassium ne-magnesium evela emzimbeni kanye nohlobo oluthe xaxa. I-Veroshpiron ingeqembu lezidakamizwa ezingathinti ukuhlushwa kwalezi zakhi zamakhemikhali. Kwezinye izimo, kuyasiza ngisho ukuyibuyisela ngokushesha ezingeni elimukelekile.
I-Veroshpiron - ukwakheka
Isithako esisebenzayo semithi echazwe yi-spironolactone. Lesi sici singumphikisi we-hormone we-mineralocorticoid, ekhishwa yizigcawu ezinama-adrenal futhi ikhuthaza ukuqoqwa kwamanzi aswakama kanye nosawoti we-sodium ezinhlakeni (aldosterone). Isidakamizwa iVeroshpiron ngezinhlobo ezahlukene zokukhululwa iqukethe nezinsiza ezisizayo:
- i-colloidal silicon dioxide;
- i-talc;
- i-magnesium stearate;
- i-lactose monohydrate;
- isitashi sommbila;
- i-lauryl sulfate ye-sodium;
- i-titanium dioxide;
- i-gelatin;
- idayi.
Yini iVeroshpiron?
Umphumela oyinhloko okhiqizwa yi-spironolactone yi-diuretic. Lokhu kubangela ukuhlukunyezwa okuvamile kakhulu, okusiza khona i-Veroshpiron - izenzakalo eziqhubekayo zemvelo nemvelaphi ehlukile. Isidakamizwa esinikeziwe kubhekwa njengendlela ephephile yokususa uketshezi oludlulele, ngoba aluphazamisi ne-electrolyte namanani okusawoti emzimbeni.
I-Veroshpiron - ukufundwa:
- ukuhluleka kwenhliziyo okungapheli nge-edematous syndrome;
- I-hypertension esemqoka (i-spironolactone ifakiwe ohlelweni lwezinyathelo eziyinkimbinkimbi);
- i-hyperaldosteronism yesibili ngemuva kwe- cirrhosis yesibindi , ama-ascites, izilonda ze-nephrotic nezinye izimo ze-pathological;
- i-myoplegia ye-paroxysmal;
- i-hypomagnesemia;
- I-Connes syndrome;
- hypokalemia.
Kunenye indawo lapho iVeroshpiron isetshenziselwa khona - izinkomba zokusetshenziswa zihlanganisa hyperprolactinemia. I-spironolactone inendawo yokunciphisa amandla okukhiqizwa kwe-hormone ye-horrenone. Lokhu kuvimbela ukwanda kwe prolactin, ngakho-ke kuvame ukushiwo yizinkinga zokubeletha-izidakamizwa ze-endocrinologist kanye nezinkinga ezihambisanayo zesistimu yokuzala, okubandakanya ukuhlaselwa kwe-cystic, fibrous and diffustive.
Ungathatha kanjani i-Veroshpiron?
Izingxenye kanye nesikhathi sokwelashwa nge-spironolactone kuncike ezintweni ezifunyanwe nezinye izifo ezihlobene. Isidakamizwa iVeroshpiron kwezinye izimo senziwa ngokufana ne-thiazide (loop) diuretics, ehlinzeka ngomphumela ocacile futhi osheshayo. Izingxenye kanye nobude besikhathi sokwelashwa kubalwa kuphela ngosazi. Kuyingozi ukuphuza uVeroshpiron ngokwakho - umthamo okhethwe ngokungalungile kungaholela emiphumeleni emibi. Ukuphikisana okuvamile kwemithi yama-amateur ukuphazamiseka okukhulu kwezinso zezinso.
Ungathatha kanjani i-Veroshpiron ngokuvuvukala?
Endabeni yokukhubazeka kwe-heart spironolactone Kunconywa ukuthi usebenzise izinsuku ezingu-5 zengu-100 (esiphezulu - 200) mg, ihlukaniswe izikhathi ezingu-2-3. I-Veroshpiron ngokuvuvukala ngokumelene nesizinda somfutho wegazi oqakathekile obalulekile kunqunywe inani elingu-50-100 mg kanye ngosuku. Kancane kancane (njalo ngemva kwamasonto amabili) umthamo ukwanda uze ufinyelele ku 200 mg. I-standard standard yezokwelapha okungenani izinsuku ezingu-14.
Uma ukuxubana kwenzeka ngenxa ye-cirrhosis yesibindi, i-spironolactone isetshenziswa ngokuhambisana nesilinganiso se-potassium ne-i-sodium i-urine. Uma lesi sibalo singaphezu kwe-1, ingxenye yansuku zonke ye-Veroshpiron ifika ku-100 mg. Nge-isilinganiso esingaphansi kwe-1, i-spironolactone inconywa ngenani le-200-400 mg. Umthamo wokondliwa ngamunye ozikhethile.
Ukuze uthole ukwelashwa nokuhlukunyezwa kwe-hyperaldosteronism ne-nephrotic syndrome, umthamo owodwa usuka ku-100 kuya ku-400 mg. Udokotela wakhe ubala ngesisekelo sedatha ngesimo sesifo kanye nokuhlushwa kwe-potassium egazini. Izinga lansuku zonke lithathwa izikhathi ezingu-1 noma ezi-2-4, kuye ngezinhloso zokwelashwa, izinga le-edema nokubekezela kwemithi.
Iziguli eziningi azifisi ukuphuza i-Veroshpiron - ngaphambi kokudla noma ngemuva, kodwa ukudla kunomthelela kakhulu ekusebenzeni kwemithi. Ukutholakala kwezinto eziphilayo nokugaya umoya we-spironolactone kwenyuka uma kungena emzimbeni kanye nokudla. Ochwepheshe batusa ukusebenzisa imithi ngokuqondile ngemva kokudla nokuphuza nge-0.5 izibuko zamanzi.
Ungathatha kanjani i-Veroshpiron yokulahlekelwa isisindo?
Isidakamizwa esichazwe yisidakamizwa esiqine kakhulu esiqeda ukuvuvukala okujulile nokuphefumula. Ukusebenzisa i-Veroshpiron ukulahlekelwa isisindo akunakwenzeka, akukhona nje kuphela okungafani, kodwa futhi kuyingozi. I-spironolactone ayithinti inani lemali egciniwe, kepha imane isusa umswakama owedlula umzimba. Uma usebenzisa njengendlela yokwehlisa isisindo noma "ukomisa", kungabangela izifo zesistimu ye-urinary nezinso.
I-Veroshpiron ngesikhathi sokukhulelwa
Uma iveza i-spironolactone iphikisana ne-contraindicated. Lesi sici, esine-bioavailability high, singena emkhawulweni we-placental futhi singena egazini legazi. Ngokushesha ngemva kokuzalwa, futhi, awukwazi ukuphuza i-Veroshpiron - izinkomba zokusebenzisa ngaphandle nokulahla. Isithako esisebenzayo salo muthi singena kuzo zonke izinto ze-biofluids futhi sifinyelela emakethe angu-100%, kufaka phakathi ubisi lwebele. I-Veroshpiron ekuthandeni kwezinsizwa isetshenziselwa kuphela ukwelashwa kwe-hyperprolactinaemia nezifo ezihlobene. Lolu hlu lubandakanya ukukhathazeka nokuphelelwa amandla kwe-endocrine.
UVeroshpiron uthatha isikhathi esingakanani?
Isikhathi senkambo yokwelapha sibalwa udokotela ngemva kokuxilongwa ngokuphelele. Ungathathi isikhathi eside ukuphuza i-Veroshpiron - ukusetshenziswa kwe-diuretic kwamasonto angaphezu kwangu-4 kungabangela ukuphazanyiswa ku-electrolyte, usawoti kanye nokusetshenziswa kwamanzi emzimbeni. Ukuphikisana okuvamile kwendlela enjalo yesikhathi eside yilashwa yi-urate diathesis noma hyperuricuria. I-Veroshpiron ye-Diuretic inconywa ukusebenzisa izinsuku ezingu-5-15. Lapho kukhona khona izinkomba, i-dose yesondlo esincane yomuthi ikhethiwe.
I-Veroshpiron - imiphumela emibi
Izimo ezimbi nge spironolactone azivamile, kodwa zifaka uhlu olubanzi lwezimo ze-pathological. I-Veroshpiron - imiphumela emibi yesicelo:
- ukuhlanza;
- isifo sohudo;
- isicasuli;
- i-gastritis;
- isilonda esiswini ezingxenyeni zomuthi wamathumbu;
- ukuqotshwa;
- colic emathunjini;
- ubuhlungu ku-epigastrium;
- ukwephulwa kwemisebenzi yesibindi;
- isiyezi;
- i-ataxia;
- ukulala;
- ukuphuza;
- ukudideka kokwazi;
- ukuxhuma;
- ikhanda;
- i-thrombocytopenia;
- i-agranulocytosis;
- i-megaloblastosis;
- hypercreatininaemia;
- i-hyperuricemia;
- i-alkalosis;
- i-hyponatremia;
- i-acidosis ye-metabolic;
- i-hyperkalemia;
- izwi elibi;
- i-gynecomastia;
- i-dysmenorrhea;
- ukwephulwa komjikelezo;
- i-hirsutism;
- i-metrorrhagia;
- i-amenorrhea;
- ukushaya isikhumba;
- i-urticaria;
- umkhuhlane;
- i-hypertrichosis;
- ukuhluleka kwezinso;
- i-alopecia;
- ukuxubha;
- imisipha ye-muscle.
I-Veroshpiron - ukuphikisana
Kunezifo lapho i-spironolactone engavunyelwe khona ngokuphelele, nezimo lapho zingasetshenziswa ngokuqapha. Esikhathini sokuqala, kufanele ubeke esikhundleni seVeroshpiron - isenzo sesidakamizwa sizolimaza kuphela. Ukuphikisana okuqondile kokusetshenziswa:
- i-hyperkalemia;
- Isifo sika-Addison ;
- ukungafinyeleli ngokweqile esigabeni esinzima;
- i-hyponatremia;
- ukubekezelelana kwe-lactose;
- i-anuria;
- isifo se-glucose engafanele noma ukutholwa kwe-galactose;
- ukukhulelwa;
- ukwehluleka kwe-lactase;
- uneminyaka engaba ngu-3;
- i-lactation;
- hypersensitivity kunoma yisiphi isithako esikudakamizwa.
Kwezinye izimo, udokotela kuphela oqaphela ukuthi kufaneleka kanjani ukunikeza i-Veroshpiron - izinkomba zokusetshenziswa zingabandakanya izifo ezilandelayo lapho kusetshenziswe khona ngokucophelela isidakamizwa:
- i-acidosis ye-metabolic;
- i-hypercalcemia;
- isifo sikashukela mellitus;
- Ukuvinjelwa kwe-AV;
- ukungena esikhathini;
- ukungakwazi ukusebenza kahle;
- ukungezwani kwesifo sikashukela ;
- Ukwandiswa okungavamile kwezigulane ezincelisayo;
- i-cirrhosis yesibindi;
- ukuguga.
I-Veroshpiron - izifaniso zokulungiselela
Faka esikhundleni se-diuretic ngemithi enomphumela ofanayo. Uma i-Veroshpiron inezinkomba zokusetshenziswa, ngokuvumelana ngokuvumelana ncamashi, kubalulekile ukufakazela ngokungeziwe izakhiwo ze-generic. Kufanele kuvimbele i-leaching ye-magnesium ne-potassium usawoti, kuyilapho kugcinwa ibhalansi ye-electrolyte ngendlela evamile. I-Veroshpiron - efana neziboniso ezifanayo zokusetshenziswa:
- I-spironolactone (eqondile);
- I-Epletor;
- Ukuvuselela;
- Eridanus;
- Dekriz;
- Epplepres;
- Inspra;
- Espiro.