I-17-OH progesterone yikhiqiza lesisemkhatsini yokusebenzisana kwama- hormone we-progesterone ne-17-hydroxyprepnenolone, futhi inegama eligcwele le-hydroxyprogesterone. I-hormone emzimbeni womuntu ikhiqizwa yizigulane eziyingozi, nakwabesifazane nama-ovaries, kanye ne-placenta ekukhulelwe. I-17-OH progesterone ithinta amathuba okukhulelwe, inkambo evamile yokukhulelwa nokuthuthukiswa komntwana. Uma kungabikho ukukhulelwa, izinga le-hormone emzimbeni wesifazane alibalulekile futhi liyahluka kakhulu kuye ngesigaba sokujikeleza esikhathini. Amanani aphakeme kakhulu yesikhathi sokukhulelwa, kancane kancane wehla ekuqaleni kokuya esikhathini.
Ihlaziya
Ukuhlolwa kwegazi kwe-17-OH progesterone kunqunyelwe kokubili abesifazane abadala nabantwana. Esikhathini sokuqala, lo mbhalo ukusola kwesifo sezinhlayiya ezingenasifo, ukungabi namuntu, ukwephulwa komjikelezo wokuya esikhathini, okwesibili - ukutholakala kwe-adrenogenital syndrome. Ngenhloso yokuhlaziywa kuncike esikhathini sokuthatha i-pro-proton-17-OH. Njengomthetho, abesifazane bahlolwe i-progesterone 17-OH 3-4 izinsuku emva kokuqala kokuya esikhathini, izingane - ekuseni ngesisu esingenalutho.
Imiphumela yokuhlaziya
Kunezinhlobo ezimbili zokuhlukahluka emiphumeleni:
- Amazinga aphezulu we-hormone akhombisa ukuthi kungenzeka izicubu zama-ovari nama-gland adrenal. Futhi, i-pro-progestone ephezulu ye-17-OH iyimbangela yokungahleleki kokuya esikhathini nokungasebenzi. Ezinganeni, izinkomba eziphakanyisiwe zikhombisa ukuthi kungenzeka yini ukuthi izifo eziphilayo zakhiwe ngokuphathelene nokukhiqizwa kwe-hormone engafanele.
- Izinga eliphansi le-hormone libonisa umsebenzi okwanele wama-ovari noma izifo ze-cortex e-adrenal. Kufanele kuqaphele ukuthi amazinga e-hormone aphansi kakhulu anciphisa amathuba okukhulelwa okuphumelelayo, ngakho-ke adinga ukulungiswa okudingekayo ngemikhiqizo yezokwelapha.