Ingane yakho yagula, kanti udokotela wabeka ukuhlolwa kwegazi jikelele. Ngokusho kwemiphumela yakhe, kwatholakala ukuthi igazi lomntwana liye landa izinga le-alkaline phosphatase. Ngokuqinisekile, abazali bazibuza ukuthi yini i-alkaline phosphatase eyabangela nokuthi iyiphi inkomba.
Yini i-alkaline phosphatase ebonisa?
I-alkaline phosphatase iyiqembu lama-enzyme equkethe cishe zonke izicubu zomzimba womuntu. I-phosphatase eningi yama-alkaline itholakala emathanjeni amathambo, ama-osteoblasts, ama-bile. Umthamo omkhulu ubizwa ngokuthi yi-mucosa yamathumbu. I-alkaline phosphatase ikhiqizwa ungqimba lwangaphakathi lwe-mucosa emathunjini, kodwa libandakanya kuphela izinqubo zokugaya okwesibili. Umsebenzi oyinhloko we-alkaline phosphatase yi-cleavage ye-phosphoric acid, edingekayo emzimbeni, kusuka ezihlukahlukene ze-organic compounds. Le enzyme ibuye ibuye ihambise ukuthuthwa kwe-phosphorus kuwo wonke umzimba.
Okuqukethwe okulandelayo kwe-alkaline phosphatase ezinganeni kubhekwa njengokujwayelekile:
- ngesikhathi sokuzalwa -
- ngosuku lwesishiyagalolunye emva kokuzalwa -
- kusukela ezinsukwini ezingu-6 kuya ezinyangeni ezingu-6 -
- kusukela ezinyangeni ezingu-6 kuya ku-1 ngonyaka -
- kusukela ngonyaka owodwa kuya eminyakeni emithathu -
- kusukela eminyakeni engama-4 kuya kwengu-6 -
- kusukela eminyakeni engu-7 kuya eminyakeni engu-12 -
- kusukela eminyakeni engu-13 kuya kweyengu-17 (abafana) -
- kusukela eminyakeni engu-13 kuya kwengu-17 (amantombazane) -
Amazinga ale enzyme e-serum yegazi angase ahluke kancane kuye ngokuthi izindlela zocwaningo kanye nama-reagents asetshenzisiwe.
Ekusebenzeni kwezingane, uhlolo lomsebenzi we-alkaline phosphatase ludlala indima ebalulekile ekuxilongweni kwesifo sesibindi, ehambisana nokuncipha kwe-bile ukugeleza kuya kwe-duodenum. Kulokhu, i-alkaline phosphatase egazini yengane ivame ukukhula. Izinga eliphakeme kakhulu le-phosphatase lenzekile uma kuphulwa ukuphuma kwebhili ngenxa yamatshe e-bile duct noma emathunjini e-bile. Ngaphezu kwalokho, nge-alkaline phosphatase yengane ephakeme, udokotela angakwazi ukubeka izifo ezinjalo:
- izifo zethambo, kuhlanganise nezicubu, i-sarcoma, i-metastases yomdlavuza ethambo;
- hyperparathyroidism;
- ukunqotshwa kwamathambo nge-lymphogranulomatosis;
- i-rickets;
- Isifo se-Paget (isifo samathambo);
- i-mononucleosis esithathelwanayo;
- i-myeloma;
- i-cytomegaly yezingane;
- izifo zamathumbu.
Okubaluleke kakhulu yikhombisi ye-alkaline phosphatase ezinganeni ukuze kutholakale ukuthi i-rickets iyatholakala yini. Kulokhu, umsebenzi we-enzyme ukhula isikhathi eside ngaphambi kokuba kuvele izibonakaliso zomtholampilo zesifo.
Ngezinye izikhathi kukhona umzimba, okungukuthi, wemvelo, ukwanda ezingeni lika-alkaline phosphatase e-serum yegazi: ezinsana ezingakabiphi noma ezintsheni ngesikhathi sokukhulelwa nokukhula okujulile kwamathambo esithambo.
Uma usebenzisa izidakamizwa ezine-side effect ye-hepatotoxic, izinga le-enzyme alkaline phosphatase enganeni lingaphakanyiswa. Lezi zidakamizwa zihlanganisa i-paracetamol, i-penicillin, i-sulfonamides, i-erythromycin nabanye abaningi. Njengoba i-metabolism ekhuphukile emathanjeni amathambo ngenkathi kutholakala ama-bone fractures, izinga le-enzyme livame ukuphakama.
Ukunciphisa izinga le-enzyme alkaline phosphatase akuyona into ebalulekile emtholampilo. Ukunciphisa ezingeni le-enzyme kungaba nokuhlukumezeka okuhlukahlukene kokukhula kwethambo, ukuntuleka kokudla ku-zinc, i-magnesium, amavithamini C no-B12, ne-anemia ne-hypothyroidism,
Indlela yokunciphisa i-alkaline phosphatase?
Ukuze isibonakaliso sezinga le-alkaline phosphatase enganeni libuyele evamile, kubalulekile ukuphatha isifo esiyisisekelo, hhayi nje ukulungisa leli zinga ngendlela evamile.
Ezinganeni, umsebenzi we-alkaline phosphatase uhlale uphakeme kunabantu abadala. Kwezinye izimo, ukunyuka komsebenzi we-phosphatase yiyona kuphela isibonakaliso sesifo esibi esiyisibindi. Ngakho-ke, kubaluleke kakhulu ukwenza zonke izifundo ezidingekayo zomtholampilo bese uqala ukwelashwa kwengane yakho ngesikhathi, okuzoholela ekutheni uphuthume ngokushesha.