I-Warfarin i-anticoagulant yesenzo esingavamile, esivela ku-coumarin. Isidakamizwa sithinta kakhulu isibindi sezinto ezincike ekuxhaseni kwe-vitamin-K. Ukuhlushwa kwalezi zinto kuncishisiwe futhi, ngokufanele, i-coagulability yegazi iyancipha. Isilinganiso uma uthatha iWarfarin kufanele sibe nenembile kakhulu. Ngaphezu kwalokho, iziguli ezithatha le mithi zidinga ukuhlolwa kwegazi njalo ukuqinisekisa ukuthi i-INR (isibalo segazi, esichaza i-coagulability yayo). Ukweqa ngokweqile noma ukungena okungalungile kwe-warfarin kungabangela ukuphuma kwangaphakathi neminye imiphumela emibi yokwehlukana okukhulu, kuze kube semphumela obulalayo.
Imiphumela emibi ye-Warfarin
Phakathi nokuphathwa kwezidakamizwa, lokhu okulandelayo kungabonwa:
- Ukwehla - okuvame ukuhlangana nokusetshenziswa komphumela we-Warfarin. Ngendlela emnene inganciphiswa ngamagciwane okugaya noma ukwakheka kwe-hematomas encane esikhumbeni. Ezimweni ezingavamile, i-anemia necrosis yendawo yesikhumba ngenxa ye-thrombosis ingenzeka. I-Internal, futhi ikakhulukazi isifo esesongela isifo sengculaza ukungasebenzi, ngokubheka umthamo wokuthatha iWarfarin, kubonakala ngamacala angu-1 000, futhi ngokuvamile kuvame ukuhlotshaniswa nokutholakala komfutho wegazi ophezulu nokunye okunye okubangelwa yi-comorbidities.
- Kusukela ohlelweni lokugaya kungagcinwa isicashu, ihudo, ukuhlanza, ubuhlungu besisu. Ezimweni ezingavamile - ukuthuthukiswa kwe-jaundice.
- Esikhathini sesimiso sezinzwa, ezimweni ezingavamile, kungenzeka ukuthi ukhathala okwedlulele, ikhanda, isizungu, kanye nokuphazamiseka kokunambitheka.
- Ezimweni ezingavamile kakhulu nge ukwelashwa isikhathi eside nge-warfarin, kunezinkinga ezivela ohlelweni lokuphefumula: ukubalwa kwe-tracheal noma i-tracheo-bronchial calcification.
- Nge-hypersensitivity ngayinye noma ukungabekezelelani kwezidakamizwa, ukuqhuma isikhumba, ukuwashaza, i-dermatitis, i- vasculitis , i-alopecia (ukulahleka kwezinwele) kungabonwa.
Overdose Warfarin
Ukuphumelela ekwelapheni umthamo wezidakamizwa kuseduze kokuphuma kwegazi, yingakho ukulawulwa kwe-INR nokuhambisana nemithi enqunyiwe ekwelapheni i-warfarin kudlala indima enkulu kangaka. Ngokwemifino encane, ngokuvamile umuthi uyadlula noma umthamo wehlisiwe. Uma ukudlula ngokweqile okuhambisana nokuthuthukiswa kwegazi elinamandla, sebenzisa i-vitamin K enomzimba (ukungatholakali umphumela we-Warfarin), kanye ne-plasma entsha eneqhwa noma i-coagulation factor concentrates.
Ukulawulwa kwe-INR ngenkathi kuthatha i-Warfarin
I-MNO yi-ratio ejwayelekile yomhlaba jikelele, isici sokuvala, esibalwa kusukela ku-prothrombin index. Ngaphandle kwalesi sibonakaliso sinciphile, igazi liyancipha futhi kunengozi enkulu yezindwangu zegazi. I-MNO ephezulu ibonisa ingozi yokuphuma kwegazi. Esikhathini sokuqala, lapho ukhetha umthamo owudingekayo wezidakamizwa, isibonakaliso sibalwa nsuku zonke. Esikhathini esizayo kunconywa ukuqhuba ukuhlaziywa kanye ngesonto, kanti uma izilinganiso ezingu-3-4 zihlala ngaphakathi kwendabuko evumelekile, imvamisa yesilingo se-INR singancishiswa kanye kanye emavikini amabili. Ukuhlaziywa okwengeziwe ku-INR kuyadingeka uma kwenzeka ushintsho ekudleni, ukucindezeleka, nezinye izinto ezingathinta inkomba.
Ukudla uma uthatha i-Warfarin
Ukudla okunomuthi omkhulu wevithamini K kunganciphisa ukusebenza komuthi. Inani elikhulu lala mavithamini litholakala emifino enhle, ngakho ekulashweni akufanele kusetshenziswe kabi ngemikhiqizo efana nalokhu:
- i-avocado;
- iklabishi;
- anyanisi;
- cilantro;
- i-parsley;
- ukhukhamba (mhlawumbe ihlanzwa, ngoba i-vitamin iyatholakala esikhumbeni), i-chicory;
- i-mint;
- kiwi izithelo;
- isaladi;
- amafutha omnqumo;
- i-peas;
- i-soybean;
- i-pistachios;
- okubomvu olwandle olubomvu;
- isipinashi.
Warfarin no-alcohol
Utshwala luthuthukisa umphumela we-anticoagulant we-warfarin futhi ngenxa yalokho, ukuvela kwegazi elingaguquki kungase kwenzeke ngisho nokuhlukunyezwa okuncane okusemakhaya. Ukuthatha umthamo omkhulu wotshwala kanye ne-warfarin kubhekene nokuthuthukiswa kokuphuma kwegazi ngaphakathi, ikakhulukazi kwesisu, okuyinto esongela ukuphila.