Le hormone ye-peptide ikhiqizwa ngogesi we-thyroid futhi igcina izinga elivamile le-calcium, ivuselela imetabolism yamaminerali, igcina ubuqotho bamathishu amathanga futhi ivuselele ukuvuselelwa kwayo. I-calcitonin ye-hormone, evamile kubesifazane abanikezwa kulesi sihloko, igcina isimo samathambo uma kwenzeka isidingo esiphuthumayo emzimbeni. Ukwengeza, ukulandelela le nkhomba kukuvumela ukuba ubone umdlavuza wegciwane bese unquma isimo sezinhlayiya ze-mammary.
I-Calcitonin yinto evamile kubesifazane
Udokotela ufundisa isiguli ukuthi angene ngaphansi kwalokhu kuhlolwa:
- ukuhlonza umdlavuza we -roid;
- ukuhlukanisa izifo ezihlobene nokushintshaniswa kwe-calcium;
- incazelo yokukhiqiza izicubu;
- ukutholakala kwe-osteoporosis ngemuva kokwelapha ukwelashwa kwe-medullary carcinoma;
- nge-fractures njalo nezibonakaliso zesifo sefu.
Igazi le-Venous lithathwa ukuze lihlaziywe, elihlolwe ngezindlela ezimbili:
- I-ELISA (i-enzyme immunoassay);
- IHL (i-immunochemiluminescent analyzer).
Izinga le-hormone liyakuthinta ubulili, iminyaka yesiguli, kanye ne-laboratory indlela esebenzayo.
I-Calcitonin ekuhlaziyweni kwegazi ngendlela yokuqala inemingcele elandelayo yendlela evamile:
- abesifazane - hhayi ngaphansi kuka -007 futhi abangaphezu kuka-12,97 pg / ml
- ngamadoda, inani kufanele libe phakathi kuka-0.68 no-32.26 pg / ml.
Uma usebenzisa i-IHL, lezi zibalo zibhekwa njengejwayelekile:
- ngamadoda angaphansi kuka 2.46 pg / ml;
- kubamele abesifazane, ukuhlushwa akukona kuka 1.46 pg / ml.
Njengoba usukhulile, lezi zinkomba ziqala ukwehla ngokuphawulekayo, kodwa namanje kufanele zihlale emingceleni evamile. I-calcma-norin ye-Norma egazini labesifazane abakhulelwe iyakhula, kodwa emva kokubeletha nokudla kudinga izinga elizinzile. Futhi, inani eliphakeme le-hormone ezinsana ezisanda kuzalwa alisho ukuthi kukhona ukukhubazeka.
I-Calcitonin - okungavamile
Le hormone idlala indima ye-oncomarker, okukuvumela ukuba uhlolisise ngokunembile. Ukudlula amanani avunyelwe kubonisa:
- umdlavuza we-thyroid ;
- i-oncology yamaphaphu, i-prostate, isifuba;
- i-anemia;
- hyperplasia.
Uma ngemuva kokususwa kokubunjwa kwe-tumor izinga le-hormone lihlala liphakeme, khona-ke imbangela ingase ibe yi-metastases. Ukugxuma okubukhali kumanani we-calcitonin kusikisela ukubuyela emuva.
Ngaphezu kwalokho, ukuphambuka kusuka kwendabuko kwenzeka lapho isiguli sinesifo esinjengokuthi:
- i-thyroiditis;
- i-pancreatitis;
- izinkinga nezinso nesibindi;
- i-anemia enonya .
Okuqukethwe okuphansi kwe-hormone kubonakala nge-resection ye-gland yegland, ngenxa yalokho inani lazo zonke ama-hormone akhiqizwa yilesi sitho kunciphisa. Futhi, lesi senzakalo sibonakala kulabo ababhekene ne-osteoporosis.