Ama-microbes kanye nama-bacterium abe izimbangela zezifo ezinzima zesistimu yokuphefumula, uhlelo lwe-urogenital nezinye izingxenye zomzimba. I-fluoroquinolones yesizukulwane sakamuva iyakubhekana ngokuphumelelayo nayo. Lezi zidakamizwa ezilwa ne-antimicrobial zikwazi ukunqoba ngisho nezifo ezingamelana ne-quinolones ne-fluoroquinolones, ezisetshenziswa eminyakeni eminingana edlule.
Fluoroquinolones 4 izizukulwane - hlobo luni lwezidakamizwa?
Ama-fluoroquinolones asetshenziselwe ukulawula ama-microbes kusukela ngawo-1960, ngesikhathi lapho amabhaktheriya abonakala evikelekile eminingi yalezi zidakamizwa. Yingakho ososayensi bengabeki lapho futhi bakhiqize izidakamizwa ezintsha nezintsha, bekhulise ukusebenza kwabo. Nanka amagama e-fluoroquinolones wesizukulwane sokugcina kanye nabandulelayo:
- Ukulungiselela isizukulwane sokuqala (i-nalidixic acid, oxolinic acid).
- Izidakamizwa zezizukulwane zesibili (i-lomefloxacin, i-norfloxacin, i-ofloxacin, i-pefloxacin, iprofloxacin).
- Ukulungiselela kwesizukulwane sesithathu (levofloxacin, parfloxacin).
- Ukulungiselela kwesizukulwane sesine (moxifloxacin, hemifloxacin, gatifloxacin, sitafloxacin, trovafloxacin).
Isenzo sesizukulwane esisha se-fluoroquinolones sisekelwe ekufakweni kwabo kwi-DNA yebhaktheriya, lapho ama-microorganisms alahlekelwa khona amandla okuphindaphinda futhi afe ngokushesha. Ngesizukulwane ngasinye, inani le-bacilli lapho izidakamizwa zisebenza khona ngempumelelo. Kuze kube manje, lokhu kungukuthi:
- E. coli;
- Pseudomonas aeruginosa ;
- induku ye-gnofilnaya;
- i-shigella;
- i-salmonella;
- ikholera stick;
- i-hominococci;
- i-meningococci;
- I-Campylobacter;
- i-chlamydia;
- i-mycoplasma;
- i-pneumococci;
- staphylococci .
Akumangalisi ukuthi ama-fluoroquinolones amaningi asemhlalweni wemithi ebaluleke kakhulu futhi edingekayo - ngaphandle kwabo akunakwenzeka ukwelapha umkhuhlane, ukwelashwa, isifo sofuba nezinye izifo eziyingozi. Ama-microorganisms kuphela lapho lolu hlobo lwemithi alukwazi ukuphazamiseka yiwo wonke ama-bacterium anaerobic.
Yini i-fluoroquinolones ezibhebheni?
Kuze kube manje, amaphilisi akhishwa nge-fluoroquinolones yokuphefumula ukuze alwe nezifo ezitholakala phezulu nangaphansi kokuphefumula, izidakamizwa zokwelashwa kwezifo ze-genito-urinary kanye
- Levofloxacin;
- I-Moxifloxacin;
- I-Sparfloxacin;
- I-Norfloxacin nabanye.
Ngaphambi kokuba uqale ukwelashwa, funda ngokucophelela ukuphikisana - izidakamizwa eziningi zaleli qembu azinconywa ukuthi zisebenzise ngokwephula umsebenzi we-excretory, izifo zezinso nesibindi. Kwabesifazane nabesifazane abakhulelwe, i-fluoroquinolones iboniswa ngokuqinile ngokwemithi kadokotela kadokotela uma kuziwa ekulondolozeni impilo.